Evidence map›Paper›PMID 35071995›Full record

ArticleBiomedical journal of scientific & technical research2021

Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis.

J Wendel, A Verma, V Dhevan, S C Chauhan, M K Tripathi

Open access · diamondAbstract read
In one paragraph

Article in Biomedical journal of scientific & technical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

J WendelDepartment of Biology, College of Sciences, The University of Texas Rio GrandeValley, McAllen, TX 78539, USA.
A VermaDepartment of Biomedical Engineering, Samrat Ashok Technological Institute, Vidisha,M.P., India.
V DhevanValley Baptist Hospital, Harlingen, TX 78550, USA.
S C ChauhanSouth Texas Center of Excellence in Cancer Research, School of Medicine, Universityof Texas Rio Grande Valley, McAllen TX 78504, USA.
M K TripathiSouth Texas Center of Excellence in Cancer Research, School of Medicine, Universityof Texas Rio Grande Valley, McAllen TX 78504, USA.
The University of Texas Rio Grande Valley · US

Funding

MUC13 Mucin in Colorectal Cancer Health DisparityR01CA204552 · NCI · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI CHAUHAN, SUBHASH C. · 2016 to 2020
$1.7M
International Conference on Cancer Health DisparitiesR13CA254453 · NCI · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI CHAUHAN, SUBHASH C., TSIN, ANDREW T C · 2020 to 2020
$20k
NCI NIH HHS R01 CA204552NCI NIH HHS R13 CA254453
6 · The paper itself

Abstract

Stress management is becoming very important part of cancer patient care. Chronic stressors lead to boost tumorigenesis and promote cancer development, recurrence, and drug resistant leading to poor health outcomes. The Hypothalamic-Pituitary-Adrenal (HPA) axis, which is activated by stress, also regulates Hypothalamic-Pituitary-Thyroid (HPT) axis. Stress related changes in immune function and inflammatory response also leads to reduced immune surveillance resulting in tumorigenesis. This article explores the hormonal axis impacted by stress and how chronic stress can lead to poor outcome of a cancer patient.

Indexed as

Cancer ProgressionCancer RecurrenceDrug ResistanceHPA AxisHPT AxisStress

Identifiers

PMID35071995
PMCPMC8782052
OpenAlexW3198204121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.