ArticleACS omega2022
Fluorescent Polypropylene Nanoplastics for Studying Uptake, Biodistribution, and Excretion in Zebrafish Embryos.
Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- A systematic review of the effects of nanoplastics on fish.Frontiers in toxicology · 2025Pooled it
- Article
- Fluorescent Labeling Strategies for Tracking Micro- and Nanoplastics in Biological Systems.Materials (Basel, Switzerland) · 2026Review
- Fluorescent nanoplastics: What steps are needed towards a representative toolkit?Microplastics and nanoplastics · 2026Review
- Microplastic Materials for Inhalation Studies: Preparation by Solvent Precipitation and Comprehensive Characterization.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Exploring Nanoplastics Bioaccumulation in Freshwater Organisms: A Study Using Gold-Doped Polymeric Nanoparticles.Nanomaterials (Basel, Switzerland) · 2025Article
- New Fluorophore and Its Applications in Visualizing Polystyrene Nanoplastics in Bean Sprouts and HeLa Cells.Molecules (Basel, Switzerland) · 2023Article
- Size-Controlled Preparation of Polyethylene Nanoplastic Particles by Nanoprecipitation and Insights into the Underlying Mechanisms.ACS omega · 2023Article
- Coronas of micro/nano plastics: a key determinant in their risk assessments.Particle and fibre toxicology · 2022Review
- Fabrication of Nylon-6 and Nylon-11 Nanoplastics and Evaluation in Mammalian Cells.Nanomaterials (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanoplastics (NPs) are emerging environmental pollutants and are a significant concern for human health. The small size of NPs allows them to accumulate within and adversely affect various tissues by penetrating the gastrointestinal barrier. However, most toxicity studies on NPs have been based on commercial polystyrene nanoparticles. Among plastics, polypropylene (PP) is one of the most widely used, and it is continuously micronized in the environment. Although PP has high potential for forming NPs by weathering, little is known about the biological effects of polypropylene nanoplastics (PPNPs) due to a lack of particle models. Here, we present a simple and high-yield method for PPNP production by nonsolvent-induced phase separation. The synthesized PPNPs were spherical in shape, with an average diameter of 562.15 ± 118.47 nm and a high yield of over 84%. These PPNPs were fluorescently labeled by the combined swelling-diffusion method to study their biodistribution after exposure to developing zebrafish embryos (ZFEs). We found that the fluorescent PPNPs were internalized by ingestion, distributed in the intestine of developing ZFEs, and eventually excreted. This study will aid evaluations of the potential risks of environmentally relevant plastics at the nanoscale.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.