Evidence map›Paper›PMID 35071822›Full record

ReviewGene reports2022

The impact of lymphoid memory cells in different ages of COVID-19 patients.

Mozhdeh Jafari, Hanieh Kolahdooz, Mahmoud Mahmoudi, Afsaneh Foolady Azarnaminy, Leila Mobasheri, Seyed-Alireza Esmaeili

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gene reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mozhdeh JafariImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Hanieh KolahdoozImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahmoud MahmoudiImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Afsaneh Foolady AzarnaminyDepartment of Anesthesiology, Social Security Organization Hospital, Ardabil, Iran.
Leila MobasheriDepartment of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyed-Alireza EsmaeiliImmunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronaviruses are highly pathogenic and transmissible viruses. The SARS-CoV-2 virus that emerged in December 2019 is increasingly recognized as a serious, worldwide public health concern. Respiratory infections and the hyper-inflammatory response induced by SARS-CoV-2 play a key role in disease severity and death in infected COVID-19 patients. However, much uncertainty still exists about the pathogenesis and various effects of COVID-19 on immune system. It seems that memory T cells can reduce the severity of COVID-19 infection by inducing a protective immune response. Memory T cells along with protective antibodies are the main defenses and also protective barrier against recurrent COVID-19 infection. The role of Memory T cells varies in different ages and the severity of COVID-19 infection varies between children, adults and the elderly. Furthermore, the aim of this review is to evaluate the role of memory cells in mild, moderate and severe infected COVID-19 patients with different ages.

Indexed as

ACE2, angiotensin-converting enzyme 2agingBALF, broncho-alveolar fluidCCL, CC-chemokine ligandCNS, central nervous systemCOVID-19COVID-19, coronavirus disease-19CRP, C-reactive proteinCRS, cytokine release syndromeCXCL, CXC-chemokine ligandEDTA, ethylenediaminetetraacetic acidICU, intensive care unitMemory B cellsMemory T cellsMNPs, mononuclear phagocytesNK, natural killer (NK) cellsSARS-CoV-2TNF, tumor necrosis factor

Identifiers

PMID35071822
PMCPMC8760633
OpenAlexW4206737299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.