Evidence map›Paper›PMID 35071788›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2022

Analysis of the disease activity of ulcerative colitis with and without concomitant primary sclerosing cholangitis: An investigation using a nationwide database in Japan.

Kota Yano, Rintaro Moroi, Hisashi Shiga, Kunio Tarasawa, Yusuke Shimoyama, Masatake Kuroha, Shin Hamada, Yoichi Kakuta, Kiyohide Fushimi, Kenji Fujimori and 2 more

Abstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kota YanoDivision of Gastroenterology, Department of Internal Medicine Tohoku University Graduate School of Medicine Sendai Japan.ORCID https://orcid.org/0000-0003-1769-1226
Rintaro MoroiDivision of Gastroenterology, Department of Internal Medicine Tohoku University Graduate School of Medicine Sendai Japan.ORCID https://orcid.org/0000-0002-6759-0135
Hisashi ShigaDivision of Gastroenterology, Department of Internal Medicine Tohoku University Graduate School of Medicine Sendai Japan.ORCID https://orcid.org/0000-0001-6623-2603
Kunio TarasawaDepartment of Health Administration and Policy Tohoku University Graduate School of Medicine Sendai Japan.
Yusuke ShimoyamaDivision of Gastroenterology, Department of Internal Medicine Tohoku University Graduate School of Medicine Sendai Japan.
Masatake KurohaDivision of Gastroenterology, Department of Internal Medicine Tohoku University Graduate School of Medicine Sendai Japan.
Shin HamadaDivision of Gastroenterology, Department of Internal Medicine Tohoku University Graduate School of Medicine Sendai Japan.
Yoichi KakutaDivision of Gastroenterology, Department of Internal Medicine Tohoku University Graduate School of Medicine Sendai Japan.ORCID https://orcid.org/0000-0002-7042-009X
Kiyohide FushimiDepartment of Health Policy and Informatics Tokyo Medical and Dental University Graduate School of Medicine Bunkyo Japan.ORCID https://orcid.org/0000-0002-1894-0290
Kenji FujimoriDepartment of Health Administration and Policy Tohoku University Graduate School of Medicine Sendai Japan.
Yoshitaka KinouchiDivision of Gastroenterology, Department of Internal Medicine Tohoku University Graduate School of Medicine Sendai Japan.
Atsushi MasamuneDivision of Gastroenterology, Department of Internal Medicine Tohoku University Graduate School of Medicine Sendai Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsPrimary sclerosing cholangitis (PSC) is a relatively common complication of ulcerative colitis (UC). Only a few studies have investigated the impact of PSC on the clinical course of UC, and their conclusions are contradictory. Therefore, we aimed to compare the disease activity of UC with and without PSC. METHODS AND

resultsWe collected UC patient data using the Diagnosis Procedure Combination database system in Japan and classified eligible admissions into two groups based on their diagnosis of either UC alone or UC associated with PSC. We then compared therapeutic details (medical treatment and surgery) between the two groups. Multivariable logistic regression analysis and propensity score matching was also performed. The rates of systemic steroid injection and infliximab administration in patients with PSC were lower than those in patients without PSC (21% vs. 28%,

conclusionUC patients with PSC might have less UC disease activity than those with UC alone.

Indexed as

infliximabprimary sclerosing cholangitissteroidulcerative colitis

Identifiers

PMID35071788
PMCPMC8762614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.