Evidence map›Paper›PMID 35071729›Full record

ArticleInformatics in medicine unlocked2022

Optimal control analysis of a COVID-19 and tuberculosis co-dynamics model.

M S Goudiaby, L D Gning, M L Diagne, Ben M Dia, H Rwezaura, J M Tchuenche

Open access · goldAbstract read
In one paragraph

Article in Informatics in medicine unlocked, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. A mathematical model for the co-dynamics of COVID-19 and tuberculosis.Mathematics and computers in simulation · 2023
    Article
  9. Article
  10. Article
  11. The COVID-19 and TB syndemic: the way forward.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Review
  12. Article
  13. Molecular and Cellular Mechanisms ofInternational journal of molecular sciences · 2022
    Review
  14. Article
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  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

M S GoudiabyDépartement de Mathématiques, UFR des Sciences et Technologies, Université Assane Seck de Ziguinchor, BP 523, Ziguinchor, Senegal.
L D GningLERSTAD, UFR Sciences appliquées et Technologie, BP 234, Université Gaston Berger, Saint-Louis, Senegal.
M L DiagneDépartement de Mathématiques, UFR des Sciences et Technologies, Université de Thies, Thies, Senegal.
Ben M DiaCollege of Petroleum Engineering and Geosciences (CPG), King Fahd University of Petroleum and Minerals (KFUPM), Dhahran 31261, Saudi Arabia.
H RwezauraMathematics Department, University of Dar es Salaam, P.O. Box 35062, Dar es Salaam, Tanzania.
J M TchuencheSchool of Computational and Communication Sciences and Engineering, Nelson Mandela African Institution of Science and Technology, P.O. Box 447, Arusha, Tanzania.
King Fahd University of Petroleum and Minerals · SANelson Mandela African Institution of Science and Technology · TZUniversité de Thiès · SNUniversité Gaston Berger · SNUniversity of Dar es Salaam · TZZiguinchor University · SN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis and COVID-19 are among the diseases with major global public health concern and great socio-economic impact. Co-infection of these two diseases is inevitable due to their geographical overlap, a potential double blow as their clinical similarities could hamper strategies to mitigate their spread and transmission dynamics. To theoretically investigate the impact of control measures on their long-term dynamics, we formulate and analyze a mathematical model for the co-infection of COVID-19 and tuberculosis. Basic properties of the tuberculosis only and COVID-19 only sub-models are investigated as well as bifurcation analysis (possibility of the co-existence of the disease-free and endemic equilibria). The disease-free and endemic equilibria are globally asymptotically stable. The model is extended into an optimal control system by incorporating five control measures. These are: tuberculosis awareness campaign, prevention against COVID-19 (e.g., face mask, physical distancing), control against co-infection, tuberculosis and COVID-19 treatment. Five strategies which are combinations of the control measures are investigated. Strategy B which focuses on COVID-19 prevention, treatment and control of co-infection yields a better outcome in terms of the number of COVID-19 cases prevented at a lower percentage of the total cost of this strategy.

Indexed as

BifurcationCo-infectionCOVID-19Optimal controlReproduction numberTuberculosis

Identifiers

PMID35071729
PMCPMC8759807
OpenAlexW4206742054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.