Evidence map›Paper›PMID 35071479›Full record

ArticleAnnals of translational medicine2021

Extracorporeal high-frequency combined with contrast-enhanced ultrasound: a novel imaging method for detection and treatment evaluation of patients with cervical trachea-associated relapsing polychondritis.

Jiaxing Tang, Weihua He, Yuxin Zhang, Qing Tang, Niantu He, Zechun Liang, Shiyue Li

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jiaxing TangNational Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Weihua HeDepartment of Ultrasound, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yuxin ZhangDepartment of Ultrasound, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Qing TangDepartment of Ultrasound, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Niantu HeDepartment of Ultrasound, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zechun LiangDepartment of Ultrasound, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Shiyue LiNational Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Guangzhou Medical University · CNState Key Laboratory of Respiratory Disease · CNFirst Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to evaluate the clinical utility of extracorporeal high-frequency ultrasound (EHFU) combined with contrast-enhanced ultrasound (CEUS) for the diagnosis and treatment of cervical trachea-associated relapsing polychondritis (CT-RP).

methodsFrom January 2013 to January 2020, 24 patients with CT-RP diagnosed clinically and pathologically were retrospectively reviewed. We used EHFU to measure the thickness of trachea cartilage and the minimum internal transverse diameter of trachea and compared it with CT. The EHFU and CEUS imaging features were compared before and after treatment and used to evaluate the effects of therapy.

resultsEHFU revealed the entire cervical tracheal cartilage (136 rings, of which 124 were abnormal). The average thickness of the 124 tracheal cartilage rings was 3.657±0.52 mm on EHFU and 3.32±0.76 mm on CT (

conclusionsEHFU combined with CEUS clearly and quickly revealed the CT-RP cervical tracheal wall, diameter of the trachea, and microstructural changes in tracheal cartilage. The effects of treatment can be reliably assessed by measuring reductions in tracheal cartilage thickening and echo changes before and after treatment. Dynamic monitoring of the condition provides timely and detailed information on cervical tracheal wall lesions and is valuable for clinical evaluation.

Indexed as

computed tomography (CT)contrast-enhanced ultrasound (CEUS)damaged tracheal cartilageextracorporeal high-frequency ultrasound (EHFU)Relapsing polychondritis (RP)

Identifiers

PMID35071479
PMCPMC8756207
OpenAlexW4205110997

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.