Evidence map›Paper›PMID 35071410›Full record

ArticleAnnals of translational medicine2021

Veronika Shavlokhova, Michael Vollmer, Andreas Vollmer, Patrick Gholam, Babak Saravi, Jürgen Hoffmann, Michael Engel, Jens Elsner, Florian Neumeier, Christian Freudlsperger

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Veronika ShavlokhovaDepartment of Oral and Maxillofacial Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Michael VollmerDepartment of Oral and Maxillofacial Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Andreas VollmerDepartment of Oral and Maxillofacial Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Patrick GholamDepartment of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Babak SaraviDepartment of Orthopedics and Trauma Surgery, Medical Centre-Albert-Ludwigs-University of Freiburg, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
Jürgen HoffmannDepartment of Oral and Maxillofacial Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Michael EngelDepartment of Oral and Maxillofacial Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Jens Elsner
Florian Neumeier
Christian FreudlspergerDepartment of Oral and Maxillofacial Surgery, University Hospital Heidelberg, Heidelberg, Germany.
University Hospital Heidelberg · DEHeidelberg University · DEStadtwerke München (Germany) · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsA surgical incision through the center of a large basal cell carcinoma (BCC) affected area in the head and face region was performed. After removing half of the tumor, the wound margins of the remaining half as well as the corresponding skin surface were scanned with an

resultsAn overall sensitivity and specificity in detection of BCC in wound margins was 88.5%, and 91.7% compared to skin surface imaging and 97.8% and 90.7%, respectively, compared to histopathology. We identified all known confocal patterns of healthy skin and BCC in wound margin scans: damage of the epidermal layer above the lesion and cellular pleomorphism, elongated and monomorphic basaloid nuclei, nuclear polarization, an increased number of dilated blood vessels with high leukocyte traffic, inflammatory cells.

conclusionsThe accuracy of

Indexed as

Basal cell carcinoma (BCC)in vivomargin assessmentreflectance confocal microscopy (RCM)

Identifiers

PMID35071410
PMCPMC8743714
OpenAlexW3213708954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.