Evidence map›Paper›PMID 35071391›Full record

ArticleFrontiers in veterinary science2021

Localization of the Serotonin Transporter in the Dog Intestine and Comparison to the Rat and Human Intestines.

Roberto Chiocchetti, Giorgia Galiazzo, Fiorella Giancola, Claudio Tagliavia, Chiara Bernardini, Monica Forni, Marco Pietra

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Intestinal serotonergic system is modulated by Toll-like receptor 9.Journal of physiology and biochemistry · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Roberto ChiocchettiDepartment of Veterinary Medical Sciences (UNI EN ISO 9001:2008), University of Bologna, Ozzano dell'Emilia, Italy.
Giorgia GaliazzoDepartment of Veterinary Medical Sciences (UNI EN ISO 9001:2008), University of Bologna, Ozzano dell'Emilia, Italy.
Fiorella GiancolaDepartment of Veterinary Medical Sciences (UNI EN ISO 9001:2008), University of Bologna, Ozzano dell'Emilia, Italy.
Claudio TagliaviaDepartment of Veterinary Medical Sciences (UNI EN ISO 9001:2008), University of Bologna, Ozzano dell'Emilia, Italy.
Chiara BernardiniDepartment of Veterinary Medical Sciences (UNI EN ISO 9001:2008), University of Bologna, Ozzano dell'Emilia, Italy.
Monica ForniDepartment of Veterinary Medical Sciences (UNI EN ISO 9001:2008), University of Bologna, Ozzano dell'Emilia, Italy.
Marco PietraDepartment of Veterinary Medical Sciences (UNI EN ISO 9001:2008), University of Bologna, Ozzano dell'Emilia, Italy.
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serotonin is crucial in gastrointestinal functions, including motility, sensitivity, secretion, and the inflammatory response. The serotonin transporter (SERT), responsible for serotonin reuptake and signaling termination, plays a prominent role in gastrointestinal physiology, representing a promising therapeutic target in digestive disorders. Serotonin transporter expression has been poorly investigated in veterinary medicine, under both healthy and pathological conditions, including canine chronic enteropathy, in which the serotonin metabolism seems to be altered. The aim of the present study was to determine the distribution of SERT immunoreactivity (SERT-IR) in the dog intestine and to compare the findings with those obtained in the rat and human intestines. Serotonin transporter-IR was observed in canine enterocytes, enteric neurons,

Indexed as

5-HTenteric nervous systemmyenteric plexusSERTsubmucosal plexus

Identifiers

PMID35071391
PMCPMC8766808
OpenAlexW4206752305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.