Evidence map›Paper›PMID 35071302›Full record

ArticleFrontiers in nutrition2021

Intestinal Microbiota and Serum Metabolic Profile Responded to Two Nutritional Different Diets in Mice.

Zhifeng Wu, Wei Cheng, Zhenyu Wang, Shuaifei Feng, Huicong Zou, Xiang Tan, Yapeng Yang, Yuqing Wang, Hang Zhang, Miaomiao Dong and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Nutrients · 2026
    Article
  2. Article
  3. Distinct gut microbiome features characterizeFrontiers in cellular and infection microbiology · 2025
    Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Zhifeng WuCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Wei ChengCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Zhenyu WangState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Shuaifei FengCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Huicong ZouCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Xiang TanCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Yapeng YangCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Yuqing WangCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Hang ZhangCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Miaomiao DongCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Yingping XiaoState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.
Shiyu TaoCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Hong WeiCollege of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China.
Huazhong Agricultural University · CNChina Agricultural University · CNZheJiang Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an interaction and bidirectional selection between dietary intake and gut microbiota due to the different efficiency of nutrients in the gut. The nutritional composition of germ-free (GF) diets differs significantly from specific pathogen-free (SPF) diets. There is, however, no data revealing how SPF animals from the same microbial background respond to them and if they affect the host. We examined the growth of SPF mice on the GF diet and found that it reduced body weight, intestinal length and intestinal morphology. Interestingly, the GF diet increased the level of pro-inflammatory bacteria in the gut of SPF mice, including Proteobacteria,

Indexed as

germ-free dietgut developmentmetabolismmicrobiotanutrient

Identifiers

PMID35071302
PMCPMC8766985
OpenAlexW4205199525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.