ReviewFrontiers in pediatrics2021
A Narrative Review on the Update in the Prevalence of Infantile Colic, Regurgitation, and Constipation in Young Children: Implications of the ROME IV Criteria.
Review in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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Who cites it
24 citing papers in PubMed, 35 citations in OpenAlex.
- Evaluating the influence of parental atopy on the effectiveness of a maternal dairy-free diet in alleviating infantile colic: a before-and-after study.BMC pediatrics · 2024Trial
- Trial
- The effect of infantile colic training given to parents on the neonatal infantile colic level and crying duration.Scientific reports · 2026Article
- Risk factors and long-term outcomes of infantile colic: A nationwide population-based study.Scientific reports · 2026Article
- Midwives' perspectives on assessing and managing mothers' distress related to excessive infant crying in Japan: a qualitative content analysis study.BMC pregnancy and childbirth · 2025Article
- Infantile Colic: When to Suspect Cow's Milk Allergy.Nutrients · 2025Review
- Labor Induction with Synthetic Oxytocin and Infantile Colic: A Case-Control Study.Medicina (Kaunas, Lithuania) · 2025Article
- Acupuncture for the treatment of infantile colic.The Cochrane database of systematic reviews · 2025Article
- Exploring Manual Interventions for Infantile Colic: A Scoping Review of the Evidence.Children (Basel, Switzerland) · 2025Review
- Supplementation of 2'-Fucosyllactose in Formula-Fed Infants Has Potential Benefits to Reduce the Risks of Infantile Colic and Atopic Dermatitis in Infancy.Pediatric gastroenterology, hepatology & nutrition · 2025Article
- Evaluating the reflux suppression properties of Gaviscon Infant powder with different milk formulations using an in vitro model of the infant stomach.Scientific reports · 2025Article
- Functional constipation in pediatric patients: an observational study in southern Brazil.Sao Paulo medical journal = Revista paulista de medicina · 2025Observational
- Understanding the probiotic health benefits ofFrontiers in microbiology · 2025Review
- Development and validation of a food and nutrition literacy questionnaire for Chinese parents of children with functional constipation (FNLQ-p).Frontiers in nutrition · 2025Article
- Altered expression of TEF gene in childhood constipation leads to a decrease in CD56American journal of translational research · 2025Article
- Exploring Community Perspectives on Functional Paediatric Habitual Constipation.International journal of environmental research and public health · 2024Article
- Rome IV Clinical Criteria and Management of Functional Constipation: Indonesian Health Care Professionals' Perspective.Pediatric gastroenterology, hepatology & nutrition · 2024Article
- Retrospective Study on the Association Between Climate Factors and Infant Colic in Beijing (2021-2022).Journal of multidisciplinary healthcare · 2024Article
- Early-Life Gut Health Indicators and Reported Prevalence of Infant Functional Constipation by Healthcare Professionals.Nutrients · 2023Article
- Effectiveness of a starch thickened infant formula with reduced lactose content, probiotics and prebiotics on quality of life and clinical outcome in infants with regurgitation and/or colic.Frontiers in nutrition · 2023Article
Corrections and comments
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Authors and funding
12 authors at 9 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regurgitation, colic, and constipation are frequently reported Functional Gastrointestinal Disorders (FGIDs) in the first few years of life. In 2016, the diagnostic criteria for FGIDs were changed from ROME III to ROME IV. This review assesses the prevalence of the most frequent FGIDs (colic, regurgitation and constipation) among children aged 0-5 years after the introduction of the later criteria. Articles published from January 1, 2016 to May 1, 2021 were retrieved from PubMed and Google Scholar using relevant keywords. A total of 12 articles were further analyzed based on the inclusion and exclusion criteria. This review consists of two studies (17%) from the Middle East, three (25%) from Asia, two (17%) from the USA, three (25%) from Europe, and one (8%) from Africa. Three studies (25%) were based on data obtained from healthcare professionals, while the rest were parent or caregiver reports. About half of the retrieved studies used the ROME IV criteria. Among infants aged 0-6 months, the reported prevalence of colic ranged between 10-15%, whilst that of regurgitation was 33.9%, and constipation was 1.5%. Among infants aged 0-12 months, the reported prevalence of regurgitation and constipation were 3.4-25.9% and 1.3-17.7%, respectively. The reported prevalence of constipation was 1.3-26% among children aged 13-48 months and 13% among children aged 4-18 years. Despite the large variations due to differences in diagnostic criteria, study respondents and age group, the prevalence of infantile colic was higher, while that for infantile regurgitation and constipation were similar using the ROME IV or III criteria.
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