Evidence map›Paper›PMID 35071047›Full record

ArticleFrontiers in cellular and infection microbiology2021

Enteropathogenic

Kaiwen Xue, Ruijie Tao, Qi Wu, Lei Zhang, Zhongyang Sun, Xing Yu, Jia Meng, Nirong Bao, Jianning Zhao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kaiwen XueDepartment of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Ruijie TaoDepartment of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Qi WuDepartment of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Lei ZhangDepartment of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Zhongyang SunDepartment of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Xing YuDepartment of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Jia MengDepartment of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Nirong BaoDepartment of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Jianning ZhaoDepartment of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
Nanjing University · CNNanjing General Hospital of Nanjing Military Command · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gut microbiota has been proven to have great effects on the regulation of bone health. However, the association between gut microbiota and particle-induced osteolysis, which is the primary cause of aseptic loosening, is still unknown. In this study, we used a combination of wide-spectrum antibiotics to eliminate the majority of gut microbiota and found that reduction of gut commensal bacteria significantly alleviated the progression of osteolysis, in which anaerobe was the biggest culprit in the exacerbation of osteolysis. Furthermore, colonization of enteropathogenic

Indexed as

Enteropathogenic Escherichia coliOsteolysisAnimalsHumansMiceMice, Inbred C57BLOsteoblastsOsteoclastsOsteogenesisSerotoninSerotonin5-HTaseptic looseningenteropathogenic E. coligut microbiotaparticle-induced osteolysis

Identifiers

PMID35071047
PMCPMC8766841
OpenAlexW4205642930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.