Evidence map›Paper›PMID 35071036›Full record

ArticleFrontiers in cellular and infection microbiology2021

Carbapenemase Production and Epidemiological Characteristics of Carbapenem-Resistant

Wan Huang, Jisheng Zhang, Lingyi Zeng, Chengru Yang, Lining Yin, Jianmin Wang, Jie Li, Xinhui Li, Kewang Hu, Xiaoli Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Characterization of Carbapenem-ResistantInfection and drug resistance · 2026
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  12. Epidemiological characteristics ofFrontiers in microbiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Wan HuangDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Jisheng ZhangDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Lingyi ZengDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Chengru YangDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Lining YinDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Jianmin WangDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Jie LiDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Xinhui LiDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Kewang HuDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Xiaoli ZhangDepartment of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Beizhong LiuCentral Laboratory of Yongchuan Hospital, Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNJiamusi University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to determine the molecular characteristics of carbapenem-resistant Methods: A total of 127 unique CRKP isolates were collected from the Yongchuan Hospital of Chongqing Medical University, identified using a VITEK-2 compact system, and subjected to microbroth dilution to determine the minimal inhibitory concentration. Enterobacteriaceae intergenic repeat consensus polymerase chain reaction and multilocus sequence typing were used to analyze the homology among the isolates. Genetic information, including resistance and virulence genes, was assessed using polymerase chain reaction. The genomic features of the CRKP carrying gene Results: ST11 was the dominant sequence type in the homology comparison. The resistance rate to ceftazidime-avibactam in children was much higher than that in adults as was the detection rate of the resistance gene Conclusion: Our study aids in understanding the prevalence of CRKP in this hospital and the significant differences between children and adults, thus providing new ideas for clinical empirical use of antibiotics.

Indexed as

Klebsiella InfectionsKlebsiella pneumoniaeAdultAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsChildChinaHumansMicrobial Sensitivity TestsPlasmidsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsantibiotic susceptibilitycarbapenem-resistant Klebsiella pneumoniaeceftazidime-avibactammolecular epidemiologyST1887whole-genome sequencing

Identifiers

PMID35071036
PMCPMC8769044
OpenAlexW4206811441

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.