Evidence map›Paper›PMID 35071034›Full record

ArticleFrontiers in cellular and infection microbiology2021

Filarial Lymphedema Patients Are Characterized by Exhausted CD4

Sacha Horn, Manuel Ritter, Kathrin Arndts, Dennis Borrero-Wolff, Anna Wiszniewsky, Linda Batsa Debrah, Alexander Y Debrah, Jubin Osei-Mensah, Mkunde Chachage, Achim Hoerauf and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Impact ofTropical medicine and infectious disease · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Sacha HornDivision of Infectious Diseases and Tropical Medicine, University Hospital Munich, Ludwig-Maximilians-Universität (LMU), Munich, Germany.
Manuel RitterInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Kathrin ArndtsInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Dennis Borrero-WolffInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Anna WiszniewskyInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Linda Batsa DebrahFilariasis Unit, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Alexander Y DebrahFilariasis Unit, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Jubin Osei-MensahFilariasis Unit, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Mkunde ChachageDivision of Infectious Diseases and Tropical Medicine, University Hospital Munich, Ludwig-Maximilians-Universität (LMU), Munich, Germany.
Achim HoeraufInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Inge KroidlDivision of Infectious Diseases and Tropical Medicine, University Hospital Munich, Ludwig-Maximilians-Universität (LMU), Munich, Germany.
Laura E LaylandInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
University Hospital Bonn · DELudwig-Maximilians-Universität München · DEKumasi Centre for Collaborative Research in Tropical Medicine · GHKwame Nkrumah University of Science and Technology · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, more than 200 million people are infected with filariae which can cause severe symptoms leading to reduced quality of life and contribute to disability-adjusted life years (DALYs). In particular, lymphatic filariasis (LF) caused by

Indexed as

LymphedemaQuality of LifeCD4-Positive T-LymphocytesDisability-Adjusted Life YearsGhanaHumansCD4+ T cell exhaustionfilariaeimmune modulationlymphatic filariasislymphedemaWuchereria bancrofti infection

Identifiers

PMID35071034
PMCPMC8770542
OpenAlexW4206102006

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.