ArticleGland surgery2021
The value of color Doppler ultrasound in the diagnosis of thyroid nodules: a systematic review and meta-analysis.
Article in Gland surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Deep learning-based classification of thyroid nodules using uncertainty-aware multi-modal ultrasound imaging.Scientific reports · 2026Article
- Comparative diagnostic performance of C-TIRADS versus Kwak TI-RADS for thyroid nodules: implications for fine-needle aspiration biopsy referral.Frontiers in endocrinology · 2026Article
- Multimodal radiomics model with triple -timepoint contrast-enhanced ultrasound for precise diagnosis of C-TIRADS 4 thyroid nodules.Frontiers in endocrinology · 2025Article
- Deep learning to assist composition classification and thyroid solid nodule diagnosis: a multicenter diagnostic study.European radiology · 2024Article
- Does color Doppler ultrasound has high value in the diagnosis of thyroid nodules?Gland surgery · 2022Article
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4 authors.
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Abstract
backgroundThis study aimed to analyze the value of color Doppler ultrasound in the diagnosis of thyroid nodules.
methodsWe searched the PubMed, Web of Science, Embase, and Cochrane Library databases for randomized controlled trials (RCTs) on using color Doppler ultrasound, thyroid nodules, thyroid tumors, and Doppler ultrasound to diagnose the thyroid nodules. The outcome indicators in the articles had to include the numbers of true positives (TP), false positives (FP), false negatives (FN), and true negatives (TN). Subsequently, the Jadad tool was adopted to evaluate the quality of the included articles, and Review Manager 5.3 software was used to conduct a meta-analysis of the experimental data.
resultsA total of eight suitable articles were selected. The results showed that the estimated sensitivity and specificity of color Doppler ultrasound for the diagnostic of thyroid nodules were 0.46-0.89 and 0.00-1.00, respectively. The pooled estimate of sensitivity for the different articles was 0.71 [95% confidence interval (CI): 0.46-0.89], and the pooled estimate of specificity was 0.77 (95% CI: 0.00-1.00). The area under the summary receiver operating characteristic (SROC) curve (AUC) was 0.917, which was larger than 0.9, signifying high diagnostic accuracy. This suggests that color doppler ultrasound can realize the clinical diagnosis of thyroid nodules. DISCUSSION: In summary, the results of this study could provide a clinical data for the promotion and application of color Doppler ultrasound in the clinical diagnosis of thyroid nodules, as well as further reliable data for follow-up clinical research on the diagnosis and treatment of thyroid nodules.
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