Evidence map›Paper›PMID 35070880›Full record

ArticleGland surgery2021

Sex disparities in thyroid cancer: a SEER population study.

Peng Li, Ying Ding, Mengyuan Liu, Wenlong Wang, Xinying Li

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gland surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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  5. Sex Differences in Cancer Stage at Diagnosis of Nonreproductive Solid Organ Tumors in the United States, 2015 to 2022.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
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  7. CHD4 and NOX4 expression in thyroid tumor tissues.Exploration of targeted anti-tumor therapy · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Peng Li *Thyroid Surgery Department, Xiangya Hospital, Central South University, Changsha, China.
Ying Ding *Thyroid Surgery Department, Xiangya Hospital, Central South University, Changsha, China.
Mengyuan LiuThyroid Surgery Department, Xiangya Hospital, Central South University, Changsha, China.
Wenlong WangThyroid Surgery Department, Xiangya Hospital, Central South University, Changsha, China.
Xinying LiThyroid Surgery Department, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence and mortality of thyroid cancer vary based on race as well as gender. Both gender thyroid cancer patients give variable clinical characteristics, such as tumor size and distant metastasis. However, sex differences in the prognosis of thyroid cancer remain controversial. Therefore, the present study explored the relationship between gender and prognosis of patients with thyroid cancer for conducive personalized treatment.

methodsA retrospective analysis was carried out on patients with pathologically proven thyroid cancer from the Surveillance, Epidemiology, and End Results (SEER) database. The gender disparities in the prognosis of different cohorts, derived by propensity score matching were investigated using Cox proportional hazards models and Kaplan-Meier curves.

resultsAmong the studied 41,270 female and 13,188 males with thyroid cancer, gender was an independent prognostic factor for overall (OS) and cancer-specific (CSS) survival (HR =1.632, 95% CI: 1.499-1.777, P<0.001; HR =1.473, 95% CI: 1.245-1.741, P<0.001). Though, male patients had a larger tumor size (17.4

conclusionsOur study demonstrated that male patients had a prognostic factor for poorer OS and CSS. Other factors including race, age, income, histological type, surgery, T, N, M stage influenced OS of male and female thyroid cancer patients. Interestingly, race had no impact on CSS of thyroid cancer patients, whereas median income affected only the male patients CSS.

Indexed as

sex disparitiesSurveillance, Epidemiology, and End Results (SEER)Thyroid cancer

Identifiers

PMID35070880
PMCPMC8749097
OpenAlexW4205531250

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.