Evidence map›Paper›PMID 35070788›Full record

ArticleCardiovascular diagnosis and therapy2021

Long-term changes after carotid stenting assessed by intravascular ultrasound and near-infrared spectroscopy.

Cyril Štěchovský, Petr Hájek, Robert Roland, Martin Horváth, Josef Veselka

Registry-linked trialAbstract read
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03141580 (Long-term Follow-up Near-infrared Spectroscopy and Intravascular Ultrasound Imaging of Internal Carotid Artery Stenosis Treated With Stenting), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03141580 nacompletednot on this map

Long-term Follow-up Near-infrared Spectroscopy and Intravascular Ultrasound Imaging of Internal Carotid Artery Stenosis Treated With Stenting

TypeinterventionalSponsorUniversity Hospital, MotolRan2017 to 2019Enrolled52ConditionsCarotid Atherosclerosis, Carotid Artery Stenting, Atherosclerotic Plaque, Near Infrared SpectroscopyArmsNear-infrared spectroscopy and intravascular ultrasound (NIRS-IVUS)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cyril ŠtěchovskýDepartment of Cardiology, Second Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
Petr HájekDepartment of Cardiology, Second Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
Robert RolandDepartment of Cardiology, Second Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
Martin HorváthDepartment of Cardiology, Second Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
Josef VeselkaDepartment of Cardiology, Second Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term effect of carotid stenting (CAS) on the stabilization of the plaque is almost unrecognized. Vascular healing and remodeling might seal the atherosclerotic plaque with neointimal hyperplasia decreasing the vulnerability. We aimed to assess long-term change in the lipid signal, stent and luminal dimensions and restenosis after CAS with the intravascular ultrasound (IVUS) and near-infrared spectroscopy (NIRS) imaging.

methodsWe performed follow-up angiography and NIRS-IVUS imaging of 58 carotid stents in 52 patients. Median time from CAS to the follow-up examination was 31 months (range, 5-56). The lipid signal of the stented segment was calculated from a NIRS-derived chemogram (a spectroscopic map) as the lipid core burden index (LCBI, a dimensionless number from 0 to 1,000). Planimetric and volumetric measurements from IVUS were performed to assess change in minimal stent area (MSA), minimal luminal area (MLA), stent and luminal volume, late stent expansion and percentage in-stent restenosis (ISR) volume.

resultsDuring the follow-up period, the mean (±SD) LCBI significantly decreased from 32±56 to 17±27 (P=0.002). The mean stent volume significantly increased from 717±302 to 1,019±429 mm

conclusionsLipid signal decreased during the follow-up period suggesting stabilization of the plaque. Late stent expansion was balanced with neointimal hyperplasia.

trial registrationThe trial is registered under clinicaltrials.gov NCT03141580.

Indexed as

Carotid stentingintravascular ultrasoundlipid core burden indexnear-infrared spectroscopyplaque stabilization

Identifiers

PMID35070788
PMCPMC8748489

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