Evidence map›Paper›PMID 35070777›Full record

ArticleWorld journal of psychiatry2021

Differential aberrant connectivity of precuneus and anterior insula may underpin the diagnosis of schizophrenia and mood disorders.

Katrin Aryutova, Rositsa Paunova, Sevdalina Kandilarova, Kristina Stoyanova, Michael Hj Maes, Drozdstoy Stoyanov

Open access · diamondAbstract read
In one paragraph

Article in World journal of psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Katrin AryutovaPsychiatry and Medical Psychology, Medical University, Plovdiv 4002, Bulgaria.
Rositsa PaunovaResearch Institute, Medical University, Plovdiv 4002, Bulgaria.
Sevdalina KandilarovaPsychiatry and Medical Psychology, Medical University, Plovdiv 4002, Bulgaria.
Kristina StoyanovaResearch Institute, Medical University, Plovdiv 4002, Bulgaria.
Michael Hj MaesResearch Institute, Medical University, Plovdiv 4002, Bulgaria.
Drozdstoy StoyanovPsychiatry and Medical Psychology, Medical University, Plovdiv 4002, Bulgaria. drozdstoy.stoyanov@mu-plovdiv.bg.
Medical University Plovdiv · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOver the past decade, resting-state functional magnetic resonance imaging (rs-fMRI) has concentrated on brain networks such as the default mode network (DMN), the salience network (SN), and the central executive network (CEN), allowing for a better understanding of cognitive deficits observed in mental disorders, as well as other characteristic psychopathological phenomena such as thought and behavior disorganization.

aimTo investigate differential patterns of effective connectivity across distributed brain networks involved in schizophrenia (SCH) and mood disorders.

methodsThe sample comprised 58 patients with either paranoid syndrome in the context of SCH (

resultsA significant excitatory connection from the dorsal anterior cingulate cortex to the anterior insula (aI) was observed in the SCH patient group, whereas inhibitory connections from the precuneus to the ventrolateral prefrontal cortex and from the aI to the precuneus were observed in the Ds group.

conclusionThe results delineate specific patterns associated with SCH and Ds and offer a better explanation of the underlying mechanisms of these disorders, and inform differential diagnosis and precise treatment targeting.

Indexed as

Bipolar disorderdefault mode networkeffective connectivityinsulaMajor depressive disorderprecuneusResting-state functional magnetic resonance imagingsalience networkSchizophrenia

Identifiers

PMID35070777
PMCPMC8717032
OpenAlexW4200294797

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.