Evidence map›Paper›PMID 35070375›Full record

ReviewJournal of thoracic disease2021

Bridge to transplantation from mechanical circulatory support: a narrative review.

Alice L Zhou, Eric W Etchill, Katherine A Giuliano, Benjamin L Shou, Kavita Sharma, Chun W Choi, Ahmet Kilic

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of thoracic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

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  3. New Insights into Cardiac Intensive Care.Reviews in cardiovascular medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Alice L ZhouJohns Hopkins School of Medicine, Baltimore, MD, USA.
Eric W EtchillDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Katherine A GiulianoDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Benjamin L ShouJohns Hopkins School of Medicine, Baltimore, MD, USA.
Kavita SharmaDivision of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Chun W ChoiDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Ahmet KilicDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Johns Hopkins Hospital · USJohns Hopkins Medicine · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo highlight recent developments in the utilization of mechanical circulatory support (MCS) devices as bridge-to-transplant strategies and to discuss trends in MCS use following the changes to the United Network for Organ Sharing (UNOS) heart allocation system.

backgroundMCS devices have played an increasingly important role in the treatment of heart failure patients. Over the past several years, technological advancements have led to new developments in MCS devices and expanding indications for MCS use. In October of 2018, the UNOS heart allocation policy was revised to prioritize higher-urgency patients, including those supported with temporary MCS devices. Since then, changes in trends of MCS utilization have been observed.

methodsArticles from the PubMed database regarding the use of MCS devices as bridge-to-transplant strategies were reviewed.

conclusionsOver the past decade, utilization of temporary MCS devices, which include the intra-aortic balloon pump (IABP), percutaneous ventricular assist devices (pVADs), and extracorporeal membrane oxygenation (ECMO), has become increasingly common. Recent advancements in MCS include the development of pVADs that can fully unload the left ventricle (LV) as well as devices designed to provide right-sided support. Technological advancements in durable left ventricular assist devices (LVADs) have also led to improved outcomes both on the device and following heart transplantation. Following the 2018 UNOS heart allocation policy revision, the utilization of temporary MCS in advanced heart failure patients has further increased and the proportion of patients bridged directly from a temporary MCS device has exponentially risen. However, following the start of the COVID-19 pandemic, the trends have reversed, with a decrease in the percentage of patients bridged from a temporary MCS device. As long-term data following the allocation policy revision becomes available, future studies should investigate how trends in MCS use for patients with advanced heart failure continue to evolve.

Indexed as

heart failureMechanical circulatory support (MCS)transplantationventricular assist device (VAD)

Identifiers

PMID35070375
PMCPMC8743412
OpenAlexW3211344515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.