Evidence map›Paper›PMID 35070213›Full record

ArticleMediterranean journal of hematology and infectious diseases2022

Coexistence of T-Large Granular Lymphocyte Leukemia and Peripheral T Cell Lymphoma-NOS with Indolent Behavior.

Luca Guarnera, Valentina Boldrini, Gianmario Pasqualone, Carolina Cimino, Elisa Meddi, Roberta Laureana, Donata Trivigno, Giovanni Del Poeta, Alessandro Mauriello, Lucia Anemona and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediterranean journal of hematology and infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Luca GuarneraHematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Valentina BoldriniHematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Gianmario PasqualoneHematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Carolina CiminoAnatomic Pathology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Elisa MeddiHematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Roberta LaureanaHematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Donata TrivignoAnatomic Pathology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Giovanni Del PoetaHematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Alessandro MaurielloAnatomic Pathology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Lucia AnemonaAnatomic Pathology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Massimiliano PostorinoHematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Maria CantonettiHematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-cell lymphomas and leukemias are highly heterogeneous groups of rare disorders. We report a case of a 68-year-old man patient who developed two different T-cell neoplasms (Large Granular Lymphocyte Leukemia [LGLL] in 2018 and Peripheral T-cell non-Hodgkin lymphoma not otherwise specified [PTCL-NOS] in 2019) with a previous diagnosis of B-cell marginal zone lymphoma in 2010, treated with two lines of chemo-immunotherapy. The coexistence of these different T-cell neoplasms is rarely reported in the literature. Moreover, it is usually described as an LGLL transformation into PTCL-NOS; differently from these examples, herein, the simultaneous conditions appear to be driven by different T-cell clones. Furthermore, the PTCL-NOS had quite unusual behavior, with good disease control without intensive treatment. Because of these features, it could belong to a subgroup of indolent PTCL-NOS, not yet described in the WHO classification of T-cell neoplasms, which could benefit from less aggressive treatment.

Indexed as

Aggressive T-cell lymphomasIndolent T-cell lymphomasLGLLPTCL-NOS

Identifiers

PMID35070213
PMCPMC8746939
OpenAlexW4205197031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.