Evidence map›Paper›PMID 35070161›Full record

ArticleEuropean journal of psychotraumatology2022

Prospective examination of pre-trauma anhedonia as a risk factor for post-traumatic stress symptoms.

Dean T Acheson, Meghan Vinograd, Caroline M Nievergelt, Kate A Yurgil, Tyler M Moore, Victoria B Risbrough, Dewleen G Baker

Open access · goldAbstract read
In one paragraph

Article in European journal of psychotraumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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  11. Trajectories of Anhedonia Symptoms after Traumatic Injury.European journal of trauma & dissociation = Revue europeenne du trauma et de la dissociation · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dean T AchesonCenter of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, USA.
Meghan VinogradCenter of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, USA.
Caroline M NievergeltCenter of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, USA.ORCID 0000-0001-5766-8923
Kate A YurgilCenter of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, USA.
Tyler M MooreDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.
Victoria B RisbroughCenter of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, USA.
Dewleen G BakerCenter of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, USA.
University of California San Diego · USLoyola University New Orleans · USUniversity of Pennsylvania · US

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
Structural & Network-Function Correlates of Fragmented Early-Life Across SpeciesP50MH096889 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARAM, TALLIE Z. · 2013 to 2023
$25.4M
Developing rodent models of PTSD/AUD: leveraging clinic-based strategiesR01AA026560 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DER-AVAKIAN, ANDRE, RISBROUGH, VICTORIA B · 2017 to 2021
$1.2M
NCATS NIH HHS UL1 TR001414NIAAA NIH HHS R01 AA026560NIMH NIH HHS P50 MH096889
6 · The paper itself

Abstract

Background: Anhedonia, the reduction of pleasure and reward-seeking behaviour, is a transdiagnostic symptom with well-described neural circuit mediators. Although typically observed during disease state, extant hypotheses suggest that anhedonia may also be an early risk factor for development of psychopathology. Understanding the contribution of anhedonia to the trauma-response trajectory may bolster inferences about biological mechanisms contributing to pre-trauma risk versus trauma-related symptom expression, knowledge of which could aid in targeted interventions. Objective: Using a prospective, longitudinal design in a population at risk for trauma disorders, we tested the hypothesis that anhedonia may be a pre-trauma risk factor for post-traumatic stress disorder (PTSD) symptoms. Methods: Adult male participants from the Marine Resilience Study ( Results: Higher pre-deployment anhedonia predicted increased PTSD intrusive re-experiencing symptoms at 3- and 6-months post-deployment when controlling for pre-trauma PTSD and depression symptoms. Depression symptoms were not significant predictors of subsequent PTSD intrusive re-experiencing symptoms. Anhedonia at 3 mo also robustly predicted maintenance of PTSD intrusive re-experiencing symptoms at the 6 mo time point. Conclusions: Pre-deployment anhedonia may be a pre-trauma risk factor for PTSD, not simply a state-dependent effect of trauma exposure and PTSD symptom expression. Anhedonia may contribute to persistence and/or chronicity of re-experiencing symptoms after the emergence of PTSD symptoms.

Indexed as

PsychopathologyAfghan Campaign 2001-AnhedoniaHumansIraq War, 2003-2011Longitudinal StudiesMaleMilitary PersonnelProspective StudiesRewardRisk FactorsStress Disorders, Post-TraumaticYoung AdultAnhedonialongitudinalmilitaryprospectivereward: post-traumatic stress disorder

Identifiers

PMID35070161
PMCPMC8774051
OpenAlexW4205936698

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.