Evidence map›Paper›PMID 35070048›Full record

ArticleWorld journal of gastrointestinal oncology2021

Hepatocellular carcinoma surveillance and quantile regression for determinants of underutilisation in at-risk Australian patients.

Elizabeth Sl Low, Ross Apostolov, Darren Wong, Sandra Lin, Numan Kutaiba, Josephine A Grace, Marie Sinclair

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PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Palliative and supportive care in patients with hepatocellular carcinoma: a qualitative study on attitudes and perceptions of health professionals.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth Sl LowDepartment of Gastroenterology and Liver Transplant Unit, Austin Health, Heidelberg 3084, Victoria, Australia. elizabeth_low312@hotmail.com.
Ross ApostolovDepartment of Gastroenterology and Liver Transplant Unit, Austin Health, Heidelberg 3084, Victoria, Australia.
Darren WongDepartment of Gastroenterology and Liver Transplant Unit, Austin Health, Heidelberg 3084, Victoria, Australia.
Sandra LinDepartment of Radiology, Monash Health, Clayton 3168, Victoria, Australia.
Numan KutaibaDepartment of Radiology, Austin Health, Heidelberg 3084, Victoria, Australia.
Josephine A GraceDepartment of Gastroenterology and Liver Transplant Unit, Austin Health, Heidelberg 3084, Victoria, Australia.
Marie SinclairDepartment of Gastroenterology and Liver Transplant Unit, Austin Health, Heidelberg 3084, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile clinical guidelines recommend hepatocellular carcinoma (HCC) surveillance for at-risk individuals, reported surveillance rates in the United States and Europe remain disappointingly low.

aimTo quantify HCC surveillance in an Australian cohort, and assess for factors associated with surveillance underutilisation.

methodsAll patients undergoing HCC surveillance liver ultrasounds between January 1, 2018 to June 30, 2018 at a tertiary hospital in Melbourne, Australia, were followed until July 31, 2020, or when surveillance was no longer required. The primary outcome was the percentage of time up-to-date with HCC surveillance (PTUDS). Quantile regression was performed to determine the impact of factors associated with HCC surveillance underutilisation.

resultsAmong 775 at-risk patients followed up for a median of 27.5 months, the median PTUDS was 84.2% (IQR: 66.3%-96.3%). 85.0% of patients were followed up by specialist gastroenterologists. Amongst those receiving specialist care, quantile regression demonstrated differential associations at various quantile levels of PTUDS for several factors. Older age at the 25

conclusionWhile median PTUDS in this Australian cohort study was 84.2%, awareness of the impact of specific factors across PTUDS quantiles can aid targeted interventions towards improved HCC surveillance.

Indexed as

Carcinoma, hepatocellularEarly detection of cancerHepatitis, viral, humanLiver cirrhosisLiver neoplasmsPopulation surveillance

Identifiers

PMID35070048
PMCPMC8713329

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