Evidence map›Paper›PMID 35070026›Full record

ArticleWorld journal of gastrointestinal endoscopy2021

Role of endoscopic ultrasound guided fine needle aspiration/biopsy in the evaluation of intra-abdominal lymphadenopathy due to tuberculosis.

Harshavardhan Rao B, Priya Nair, S Krishna Priya, Archana George Vallonthaiel, Dipu T Sathyapalan, Anoop K Koshy, Rama P Venu

Open access · diamondAbstract read
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Article in World journal of gastrointestinal endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Harshavardhan Rao BDepartment of Gastroenterology, Amrita Institute of Medical Sciences, Kochi 682041, Kerala, India.
Priya NairDepartment of Gastroenterology, Amrita Institute of Medical Sciences, Kochi 682041, Kerala, India.
S Krishna PriyaDepartment of Gastroenterology, Amrita Institute of Medical Sciences, Kochi 682041, Kerala, India.
Archana George VallonthaielDepartment of Pathology, Amrita Institute of Medical Sciences, Kochi 682041, Kerala, India.
Dipu T SathyapalanDepartment of Internal Medicine, Amrita Institute of Medical Sciences and Research Centre, Kochi 682041, Kerala, India.
Anoop K KoshyDepartment of Gastroenterology, Amrita Institute of Medical Sciences, Kochi 682041, Kerala, India. akkoshy5@gmail.com.
Rama P VenuDepartment of Gastroenterology, Amrita Institute of Medical Sciences, Kochi 682041, Kerala, India.
Amrita Institute of Medical Sciences and Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntra-abdominal lymphadenopathy due to tuberculosis (TB) poses a diagnostic challenge due to difficulty in tissue acquisition. Although endoscopic ultrasound guided fine needle aspiration/biopsy (EUS-FNA/B) has shown promise in the evaluation of mediastinal lymph nodes, its role in the evaluation of intra-abdominal lymphadenopathy is not clear.

aimTo assess the role of EUS-FNA/B in the evaluation of intra-abdominal lymphadenopathy due to TB.

methodsThis was a retrospective study where patients with intra-abdominal lymphadenopathy who underwent evaluation with EUS-FNA/B were included. TB was diagnosed if the patient had any one of the following: (1) Positive acid fast bacilli (AFB) stain/TB GeneXpert/TB-polymerase chain reaction/AFB culture of tissue sample; and (2) Positive Mantoux test and response to anti-tubercular therapy. EUS-FNA reports, clinical reports and imaging characteristics of patients were recorded for a detailed analysis of patients with TB.

resultsA total of 149 patients underwent an EUS-FNA/B from lymph nodes (mean age 51 ± 17 years, M:F = 1.2). Benign inflammatory reactive changes were seen in 45 patients (30.2%), while 54 patients (36.2%) showed granulomatous inflammation with/without caseation. Among these, 51 patients (94.4%) were confirmed to have TB as

conclusionEUS-FNA/B has a high diagnostic yield with a good sensitivity and specificity in the evaluation of intra-abdominal lymphadenopathy due to TB. However, the validity of these findings in populations with low prevalence of TB needs further evaluation.

Indexed as

Endoscopic ultrasoundIntra-abdominalLymph nodesMesentericTuberculosis

Identifiers

PMID35070026
PMCPMC8716983
OpenAlexW4200332604

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.