Evidence map›Paper›PMID 35069890›Full record

ArticleJournal of Cancer2022

Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway.

YanJie Lu, Ying Zhang, HanZheng Zhao, Qingshan Li, Ying Liu, YanZhen Zuo, Qian Xu, Hongyan Zuo, Yang Li, YuHong Li

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Dynamic screening for anxiety and depression in patients undergoing primary surgery for gastrointestinal cancer.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Effect of chronic stress on tumorigenesis and development.Cellular and molecular life sciences : CMLS · 2022
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

YanJie LuDepartment of Pathology, Chengde Medical College, Chengde, Hebei, China.
Ying ZhangDepartment of Pathology, Chengde Medical College, Chengde, Hebei, China.
HanZheng ZhaoDepartment of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Qingshan LiDepartment of oncology, The First Affiliated Hospital of Chengde Medical College, Chengde, Hebei, China.
Ying LiuDepartment of Pathology, Chengde Medical College, Chengde, Hebei, China.
YanZhen ZuoCancer Research Laboratory, Chengde Medical College, Chengde, Hebei, China.
Qian XuCancer Research Laboratory, Chengde Medical College, Chengde, Hebei, China.
Hongyan ZuoDepartment of Pathology, Chengde Medical College, Chengde, Hebei, China.
Yang LiDepartment of Pathology, Chengde Medical College, Chengde, Hebei, China.
YuHong LiDepartment of Pathology, Chengde Medical College, Chengde, Hebei, China.
Beijing Radiation Center · CNSecond Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic stress induced by long-term anxiety and depression can promote the malignant progression of gastric cancer. β2-adrenergic receptor (β2-AR) is a critical mediator for chronic stress-induced multiple processes of tumor cells. However, the function of chronic stress in gastric cancer and its potential mechanisms

Indexed as

chronic stressepithelial-mesenchymal transitionERKgastric cancersalbutamolβ2-AR

Identifiers

PMID35069890
PMCPMC8771504
OpenAlexW4200320316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.