Evidence map›Paper›PMID 35069752›Full record

ArticleMolecular & cellular toxicology2022

Hydrochloric acid-treated

Young-Min Kim, Kwang-Su Lee, Won-Mun Kim, Min Kim, Han-Oh Park, Chang Won Choi, Joong-Soo Han, Shin-Young Park, Ki-Sung Lee

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. A Chemically InducedVaccines · 2026
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  3. Differential expression ofVeterinary world · 2025
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  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Young-Min KimDepartment of Biology and Medicinal Science, Pai Chai University, Daejeon, Republic of Korea.
Kwang-Su LeeDepartment of Biology and Medicinal Science, Pai Chai University, Daejeon, Republic of Korea.
Won-Mun KimDepartment of Biology and Medicinal Science, Pai Chai University, Daejeon, Republic of Korea.
Min KimDepartment of Biology and Medicinal Science, Pai Chai University, Daejeon, Republic of Korea.
Han-Oh ParkNew Drug R&D Center, Bioneer Corporation, Daejeon, Republic of Korea.
Chang Won ChoiDepartment of Biology and Medicinal Science, Pai Chai University, Daejeon, Republic of Korea.
Joong-Soo HanBiomedical Research Institute and Department of Biochemistry and Molecular Biology, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Shin-Young ParkBiomedical Research Institute and Department of Biochemistry and Molecular Biology, College of Medicine, Hanyang University, Seoul, Republic of Korea.ORCID 0000-0002-6073-4634
Ki-Sung LeeDepartment of Biology and Medicinal Science, Pai Chai University, Daejeon, Republic of Korea.
Pai Chai University · KRHanyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bacterial ghosts (BGs) are empty cell envelopes commonly generated using Gram-negative bacteria; they represent a potential platform for efficient adjuvant and vaccine delivery systems. However, the efficient production of BGs from bacteria in a short period of time is challenging. Objective: The purpose of this study was to investigate the possibility of producing BGs in the Gram-positive Results: In this study, Conclusion: These data suggest that the HCl-induced BSGs may be potentially safe and effective candidates for inactivated bacterial vaccines and/or immunostimulants. Supplementary Information: The online version contains supplementary material available at 10.1007/s13273-022-00221-5.

Indexed as

Bacillus subtilisBacterial ghostsCytokinesHydrochloric acidMacrophages

Identifiers

PMID35069752
PMCPMC8764320
OpenAlexW4205468023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.