ArticleFrontiers in genetics2021
Evaluation of Epigenetic Age Based on DNA Methylation Analysis of Several CpG Sites in Ukrainian Population.
Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Dental Ageing Offers New Insights Into the First Epigenetic Clock for Common Dolphins (Ecology and evolution · 2025Article
- Dental aging offers new insights to the first epigenetic clock for common dolphins (bioRxiv : the preprint server for biology · 2025Article
- Novel multi-omics deconfounding variational autoencoders can obtain meaningful disease subtyping.Briefings in bioinformatics · 2024Article
- Editorial: Year in review: discussions in genetics of aging.Frontiers in genetics · 2024Article
- Development of a novel forensic age estimation strategy for aged blood samples by combining piRNA and miRNA markers.International journal of legal medicine · 2023Article
- Metabolo-epigenetic interplay provides targeted nutritional interventions in chronic diseases and ageing.Frontiers in oncology · 2023Review
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Authors and funding
6 authors.
Funding
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Abstract
Epigenetic clocks are the models, which use CpG methylation levels for the age prediction of an organism. Although there were several epigenetic clocks developed there is a demand for development and evaluation of the relatively accurate and sensitive epigenetic clocks that can be used for routine research purposes. In this study, we evaluated two epigenetic clock models based on the 4 CpG sites and 2 CpG sites in the human genome using the pyrosequencing method for their methylation level estimation. The study sample included 153 people from the Ukrainian population with the age from 0 to 101. Both models showed a high correlation with the chronological age in our study sample (R
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