Evidence map›Paper›PMID 35069447›Full record

ArticleFrontiers in endocrinology2021

Decrease in Salivary Serotonin in Response to Probiotic Supplementation With

Michał Seweryn Karbownik, Joanna Kręczyńska, Anna Wiktorowska-Owczarek, Paulina Kwarta, Magdalena Cybula, Nebojša Stilinović, Tadeusz Pietras, Edward Kowalczyk

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Potential benefits of yeastFrontiers in veterinary science · 2023
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Michał Seweryn KarbownikDepartment of Pharmacology and Toxicology, Medical University of Lodz, Łódź, Poland.
Joanna KręczyńskaDepartment of Infectious Diseases and Hepatology, Medical University of Lodz, Łódź, Poland.
Anna Wiktorowska-OwczarekDepartment of Pharmacology and Toxicology, Medical University of Lodz, Łódź, Poland.
Paulina KwartaPsychiatric Ward for Adolescents, Babinski Specialist Psychiatric Healthcare Center, Łódź, Poland.
Magdalena CybulaOklahoma Medical Research Foundation, Aging and Metabolism Program, Oklahoma City, OK, United States.
Nebojša StilinovićDepartment of Pharmacology, Toxicology and Clinical Pharmacology, University of Novi Sad, Novi Sad, Serbia.
Tadeusz PietrasDepartment of Clinical Pharmacology, Medical University of Lodz, Łódź, Poland.
Edward KowalczykDepartment of Pharmacology and Toxicology, Medical University of Lodz, Łódź, Poland.
Medical University of Lodz · PLOklahoma Medical Research Foundation · USUniversity of Novi Sad · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bacterial probiotics are thought to exert a serotonergic effect relevant to their potential antidepressant and pro-cognitive action, but yeast probiotics have not been tested. The aim of the present study was to determine whether 30-day supplementation with Methods: Healthy medical students were randomized to ingest Results: Data of thirty-two participants (22.8 ± 1.7 years of age, 16 males) was available for the main analysis. Supplementation with Conclusions:

Indexed as

ProbioticsSaccharomyces boulardiiAdultDouble-Blind MethodFemaleHealthy VolunteersHeart RateHumansMaleMetanephrineRandom AllocationSalivaSerotoninStress, PsychologicalYoung AdultMetanephrineSerotoninanxietydepressiondietary supplementationprobioticSaccharomyces boulardiisalivary serotoninsymapathoadrenal markersyeast

Identifiers

PMID35069447
PMCPMC8772029
OpenAlexW4206020823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.