Evidence map›Paper›PMID 35069292›Full record

ArticleFrontiers in psychiatry2021

Interactions Between Opioids and Dextroamphetamine on Locomotor Activity: Influence of an Opioid's Relative Efficacy at the Mu Receptor.

Mark A Smith, Shannon L Ballard, Clarise F Ballesteros, Samantha A Bonge, Alexander T Casimir, Lauren M Childs, Max A Feinstein, Annie K Griffith, Alexandra N Johansen, Daegeon Lee and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 66% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Mark A SmithProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Shannon L BallardProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Clarise F BallesterosProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Samantha A BongeProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Alexander T CasimirProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Lauren M ChildsProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Max A FeinsteinProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Annie K GriffithProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Alexandra N JohansenProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Daegeon LeeProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
A Caroline MauserProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Cassidy M MosesProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Ian J RobertsonProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Javier U RoblesProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Justin C StricklandProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Mary E WaltersProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Seeley J YooProgram in Neuroscience, Department of Psychology, Davidson College, Davidson, NC, United States.
Davidson College · US

Funding

Social Influences on Drug-Seeking BehaviorR01DA031725 · NIDA · DAVIDSON COLLEGE · PI SMITH, MARK A · 2012 to 2022
$3.1M
The Influence of Gonadal Hormones on Opioid UseR01DA045364 · NIDA · DAVIDSON COLLEGE · PI SMITH, MARK A · 2018 to 2022
$1.6M
NIDA NIH HHS R01 DA031725NIDA NIH HHS R01 DA045364
6 · The paper itself

Abstract

Opioids and stimulants are often used in combination for both recreational and non-recreational purposes. High-efficacy mu opioid agonists generally increase the behavioral effects of stimulants, whereas opioid receptor antagonists generally attenuate the behavioral effects of stimulants; however, less is known regarding the interactions between stimulants and opioids possessing low to intermediate efficacy at the mu receptor. The purpose of this study was to examine the role of an opioid's relative efficacy at the mu receptor in altering the behavioral effects of dextro(

Indexed as

addictiondrug combinationdrug interactionpharmacotherapypolydrug abuse

Identifiers

PMID35069292
PMCPMC8766790
OpenAlexW4205766367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.