Evidence map›Paper›PMID 35069183›Full record

ArticleFrontiers in pharmacology2021

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.

Stella Trompet, Iris Postmus, Helen R Warren, Raymond Noordam, Roelof A J Smit, Elizabeth Theusch, Xiaohui Li, Benoit Arsenault, Daniel I Chasman, Graham A Hitman and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Ethnic Diversity and Warfarin Pharmacogenomics.Frontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 4 countries.

Stella TrompetDepartment of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands.
Iris PostmusDepartment of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands.
Helen R WarrenWilliam Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom.
Raymond NoordamDepartment of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands.
Roelof A J SmitDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands.
Elizabeth TheuschDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, United States.
Xiaohui LiInstitute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, United States.
Benoit ArsenaultCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec City, QC, Canada.
Daniel I ChasmanDivision of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Graham A HitmanBlizard institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Patricia B MunroeWilliam Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom.
Jerome I RotterInstitute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, United States.
Bruce M PsatyCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, United States.
Mark J CaulfieldWilliam Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom.
Ron M KraussDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, United States.
Adrienne L CupplesDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, United States.
Wouter J JukemaDepartment of Cardiology, Leiden University Medical Center, Leiden, Netherlands.
Leiden University Medical Center · NLQueen Mary University of London · GBThe Lundquist Institute · USUniversity of California, San Francisco · USWilliam Harvey Research Institute · GBBoston University · USHarvard University · USInstitut Universitaire de Cardiologie et de Pneumologie de Québec · CAUniversity of Washington · US

Funding

CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5M
Medical Research Council G9521010NHLBI NIH HHS R01 HL105756
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiovascular diseaseGWASmyocardial infarctionpharmacogeneticsstatins

Identifiers

PMID35069183
PMCPMC8769168
OpenAlexW4206105036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.