Evidence map›Paper›PMID 35069017›Full record

ReviewCurrent anesthesiology reports2022

The Use of Whole Blood Transfusion in Trauma.

Mary Hanna, Justin Knittel, Jason Gillihan

Open access · bronzeAbstract readReview
In one paragraph

Review in Current anesthesiology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 55 citations in OpenAlex.

  1. The resurgence of whole blood transfusion: Evaluating microcirculatory evidence in hemorrhagic trauma care: A review.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. An analysis of blood transfusion practices in gunshot wound patients at a peripheral trauma-blood centre unit.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  6. Article
  7. Prehospital Blood Administration in Traumatic Hemorrhagic Shock.Journal of the American College of Emergency Physicians open · 2025
    Article
  8. Hemostats in the clinic.Bioengineering & translational medicine · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Massive Trauma and Resuscitation Strategies.Anesthesiology clinics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Mary HannaDepartment of Anesthesiology and Pain Medicine, University of Ottawa, The Ottawa Hospital, Ottawa, ON, CA K1S5W1 Canada.
Justin KnittelDepartment of Anesthesiology, Washington University School of Medicine, Campus Box 8054, 600 S Euclid Ave, St Louis, MO 63110 USA.
Jason GillihanDepartment of Anesthesiology, Washington University School of Medicine, Campus Box 8054, 600 S Euclid Ave, St Louis, MO 63110 USA.ORCID 0000-0001-8286-2760
Washington University in St. Louis · USOttawa Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose of Review: This review illustrates the current benefits, limitations, ongoing research, and future paths for Low Titer O Whole Blood compared to Component Therapy in massive transfusion for trauma patients. Recent Findings: Many studies show that compared to Component Therapy, Low Titer O Whole Blood transfusion is associated with better patient outcomes and simplified transfusion logistics among others. There are, however, issues with cost, supply/demand and handling of Whole Blood that limit its use, but experience in the military setting has shown that these limitations can be easily overcome. Summary: The use of Whole Blood has increased in the civilian trauma population and there is a growing body of evidence to support its current use. More research looking at Whole Blood in females of child-bearing age, pediatric populations, and cold-stored platelets is underway.

Indexed as

Component therapy (CT)Damage control resuscitation (DCR)Low Titer O Whole Blood (LTOWB)Massive transfusion protocol (MTP)Whole blood (WB)

Identifiers

PMID35069017
PMCPMC8761832
OpenAlexW4205511112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.