ArticleThe Egyptian journal of neurology, psychiatry and neurosurgery2022
Baseline predictors of progression of Parkinson's disease in a sample of Egyptian patients: clinical and biochemical.
Article in The Egyptian journal of neurology, psychiatry and neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Rate of motor progression in Parkinson's disease: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Accessible assessment of motor and cognitive symptoms in Parkinson's disease: integrating large datasets, machine-learning, and videoconferencing.NPJ digital medicine · 2026Article
- Machine Learning Predicts Risk of Falls in Parkison's Disease Patients in a Multicenter Observational Study.European journal of neurology · 2025Observational
- The p.Gly2019Ser is a common LRRK2 pathogenic variant among Egyptians with familial and sporadic Parkinson's disease.NPJ Parkinson's disease · 2024Article
- Improvements in clinical signs and symptoms of Parkinson's disease using photobiomodulation: a five-year follow-up.BMC neurology · 2024Article
- Plasma extracellular vesicle tau, β-amyloid, and α-synuclein and the progression of Parkinson's disease: a follow-up study.Therapeutic advances in neurological disorders · 2023Article
- Impact of Parkinson's Disease on Functional Mobility at Different Stages.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClinical progression of Parkinson's disease (PD) is highly heterogeneous, and its predictors are generally lacking. Identifying predictors of early disease progression is important for patients' management and follow-up. The current study aims to identify clinical, neuroimaging and biochemical baseline predictors of motor progression in patients with PD. Forty-five PD patients were assessed at baseline, 6 months and 1 year using MDS-UPDRS total and subscores, Hoehn and Yahr (H&Y), Schwab and England (S&E), International Physical Activity Questionnaire (IPAQ). Baseline New Freezing of Gait Questionnaire (NFOG-Q), Berg Balance Scale (BBS), Ten-Meter Walking Test (10-MWT)
resultsSignificant worsening of MDS-UPDRS total, part III scores, H&Y, S&E and IPAQ (
conclusionDespite the significant motor and physical activity progression over 1 year that was correlated to baseline motor and gait severity, but without predictive value, further similar and longitudinal studies are warranted to detect predictors of early progression and confirm findings. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s41983-022-00445-1.
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