Evidence map›Paper›PMID 35068792›Full record

ArticleJournal of clinical and experimental hepatology

Prevalence, Predictors, and Outcomes of Esophageal

Nipun Verma, Saurabh Mishra, Shreya Singh, Arka De, Madhumita Premkumar, Sunil Taneja, Ajay Duseja, Virendra Singh

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Fungal infections in liver cirrhosis.Translational gastroenterology and hepatology · 2024
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nipun VermaDepartments of Hepatology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India.
Saurabh MishraDepartments of Hepatology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India.
Shreya SinghDepartments of Medical Mycology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India.
Arka DeDepartments of Hepatology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India.
Madhumita PremkumarDepartments of Hepatology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India.
Sunil TanejaDepartments of Hepatology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India.
Ajay DusejaDepartments of Hepatology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India.
Virendra SinghDepartments of Hepatology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal candidiasis is often neglected and potentially serious infection in cirrhosis patients. Therefore, we evaluated the prevalence, risk factors, and outcomes of esophageal candidiasis (EC) in cirrhotics and did a systematic review to summarize EC's available evidence in cirrhosis.

methodsConsecutive patients with cirrhosis posted for esophagogastroduodenoscopy (EGD) at a tertiary care institute were screened for EC (cases) between January 2019 and March 2020. EC was diagnosed on EGD findings and

resultsEC was diagnosed in 100 of 2762 patients with cirrhosis (3.6%). Patients with EC had a higher model for end-stage liver disease (MELD) (12.4 vs. 11.2;

conclusionsEC is not a rare infection in cirrhosis patients, and it may predispose to invasive candidiasis and untimely deaths. Alcohol binge, HCC, UGI bleed, ACLF, diabetes, and higher MELD are the independent predictors of EC in cirrhosis. At-risk patients with cirrhosis or those with deglutition symptoms should be rapidly screened and treated for EC.

Indexed as

ACLFACLF, Acute-on-chronic liver failureAIC, Akaike's Information CriteriaAIDS, Acquired Immunodeficiency SyndromeBIC, Bayesian Information CriteriaCandidacirrhosisDM, Diabetes MellitusEC, Esophageal CandidiasisEGD, EsophagogastroduodenoscopyesophagitisEVL, Endoscopic Variceal LigationHAART, Highly Active Anti-Retroviral TherapyHCC, Hepatocellular CarcinomaHIV, Human Immunodeficiency VirusIC, Invasive Candidiasisinvasive fungal infectionsMELD, Model for End-stage Liver DiseaseMELD-Na, Model for End-stage Liver Disease-SodiumRRT, Renal Replacement TherapySBP, Spontaneous Bacterial PeritonitisSIRS, Systemic Inflammatory Response SyndromeUGI, Upper Gastrointestinal

Identifiers

PMID35068792
PMCPMC8766531
OpenAlexW3135922254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.