Evidence map›Paper›PMID 35068427›Full record

ArticleTechnology and health care : official journal of the European Society for Engineering and Medicine2022

Role of patient-specific blood properties in computational fluid dynamics simulation of flow diverter deployed cerebral aneurysms.

Yuya Uchiyama, Soichiro Fujimura, Hiroyuki Takao, Takashi Suzuki, Toshihiro Ishibashi, Katharina Otani, Kostadin Karagiozov, Koji Fukudome, Hideki Yamamoto, Makoto Yamamoto and 1 more

Abstract read
In one paragraph

Article in Technology and health care : official journal of the European Society for Engineering and Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Hemodynamics in Cerebral Aneurysms and Parent Arteries With Incompletely Expanded Flow Diverter Stents.International journal for numerical methods in biomedical engineering · 2025
    Article
  3. Article
  4. Experimental study using phantom models of cerebral aneurysms and 4D-DSA to measure blood flow on 3D-color-coded images.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuya UchiyamaGraduate School of Mechanical Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, Japan.
Soichiro FujimuraDepartment of Innovation for Medical Information Technology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Hiroyuki TakaoGraduate School of Mechanical Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, Japan.
Takashi SuzukiDepartment of Innovation for Medical Information Technology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Toshihiro IshibashiDepartment of Neurosurgery, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Katharina OtaniDepartment of Neurosurgery, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Kostadin KaragiozovDepartment of Neurosurgery, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Koji FukudomeDepartment of Mechanical Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, Japan.
Hideki YamamotoFaculty of Environmental and Urban Engineering, Kansai University Fukita-shi, Osaka, Japan.
Makoto YamamotoDepartment of Mechanical Engineering, Tokyo University of Science, Katsushika-ku, Tokyo, Japan.
Yuichi MurayamaDepartment of Neurosurgery, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemodynamics and their clinical outcome of cerebral aneurysms treated with flow diverter (FD) stents have thus far been investigated using computational fluid dynamics (CFD) simulations. Although human blood is characterized as a non-Newtonian patientspecific fluid, non-patient-specific blood properties (PSBP) were applied in most extant studies.

objectiveTo investigate the hemodynamic effects caused by PSBPs in aneurysms treated with FD stents.

methodsWe measured blood properties (density and viscosity) for 12 patients who underwent FD stent deployment. We conducted CFD simulations with the measured PSBPs and non-PSBPs quoted from previous studies. The average blood flow velocity and wall shear stress within the aneurysms were calculated and two simulation patterns were compared.

resultsThe velocity and wall shear stress changed by 2.93% and 3.16% on average, respectively, without an FD stent deployed. Conversely, with the FD stents deployed, the change rates increased to 11.1% and 9.06% on average, respectively.

conclusionsThe change in hemodynamic parameters if PSBPs are considered, may not be negligible when conducting CFD simulations of FD stent deployed aneurysms To obtain an adequate hemodynamic environment for cerebral aneurysms with FD stents deployed, it is recommended to use PSBPs for CFD simulations.

Indexed as

Intracranial AneurysmComputer SimulationHemodynamicsHumansHydrodynamicsStentsblood flow simulationCFDflow diverter stentHemodynamicsnon-Newtonian fluidpatient-specific blood propertiesvelocitywall shear stress

Identifiers

PMID35068427
PMCPMC9398066

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.