Evidence map›Paper›PMID 35068086›Full record

ArticleAnnals of clinical and translational neurology2022

Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report.

Ashraf S Gorgey, Tommy W Sutor, Jacob A Goldsmith, Areej N Ennasr, Timothy D Lavis, David X Cifu, Robert Trainer

Abstract readCase Reports
In one paragraph

Article in Annals of clinical and translational neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashraf S GorgeySpinal Cord Injury and Disorders Center, Hunter Holmes McGuire VAMC, 1201 Broad Rock Boulevard, Richmond, Virginia, 23249, USA.ORCID 0000-0002-9157-6034
Tommy W SutorSpinal Cord Injury and Disorders Center, Hunter Holmes McGuire VAMC, 1201 Broad Rock Boulevard, Richmond, Virginia, 23249, USA.ORCID 0000-0001-5072-3184
Jacob A GoldsmithSpinal Cord Injury and Disorders Center, Hunter Holmes McGuire VAMC, 1201 Broad Rock Boulevard, Richmond, Virginia, 23249, USA.ORCID 0000-0002-1699-4092
Areej N EnnasrSpinal Cord Injury and Disorders Center, Hunter Holmes McGuire VAMC, 1201 Broad Rock Boulevard, Richmond, Virginia, 23249, USA.
Timothy D LavisSpinal Cord Injury and Disorders Center, Hunter Holmes McGuire VAMC, 1201 Broad Rock Boulevard, Richmond, Virginia, 23249, USA.
David X CifuDepartment of Physical Medicine & Rehabilitation, Virginia Commonwealth University, Richmond, Virginia, 23298, USA.
Robert TrainerPhysical Medicine and Rehabilitation, Hunter Holmes McGuire VAMC, 1201 Broad Rock Boulevard, Richmond, Virginia, 23249, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A male with C7 complete tetraplegia participated in 14 weeks of body weight supported treadmill training (BWSTT) combined with spinal cord epidural stimulation (SCES), 4 weeks of no intervention, and two more weeks of BWSTT + SCES. The participant presented with unstable resting seated blood pressure (BP; 131/66 mmHg). After retrospective analysis, resting systolic BP decreased and diastolic BP increased, yielding a safe mean arterial BP. There was a fivefold increase in BWSTT bouts per session, and percentage of body weight support decreased to 69%. BWSTT + SCES safely and effectively regulated resting BP and mitigated symptoms of orthostatic intolerance. These effects were not maintained after 4 weeks without training.

Indexed as

Exercise TherapyNeurological RehabilitationSpinal Cord StimulationAdultBlood PressureCombined Modality TherapyEpidural SpaceHumansMaleQuadriplegia

Identifiers

PMID35068086
PMCPMC8862417

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.