Evidence map›Paper›PMID 35067815›Full record

ReviewMolecular biology reports2022

The significance of the SDF-1/CXCR4 signaling pathway in the normal development.

Farzad Sadri, Zohreh Rezaei, Mohammad Fereidouni

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 70 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Monocyte Migration Emerges from a Divergent Chemokine Signaling Network.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. The meningeal-cerebellar axis: a new perspective on cerebellar development.Cellular and molecular life sciences : CMLS · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Farzad SadriStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.ORCID http://orcid.org/0000-0003-4353-9412
Zohreh RezaeiDepartment of Biology, University of Sistan and Baluchestan, Zahedan, Iran.
Mohammad FereidouniCellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran. dr.m.fereidouni@gmail.com.
Birjand University of Medical Sciences · IRUniversity of Sistan and Baluchestan · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokines are chemoattractants that can regulate cell movement and adhesion. SDF-1 [stromal cell-derived factor-1 (SDF-1)] is a homeostatic CXC chemokine. SDF-1 and its receptors [CXC chemokine receptor 4 (CXCR4)] form a signaling pathway that plays critical roles in different pathological and physiological mechanisms, including embryogenesis, wound healing, angiogenesis, tumor growth, and proliferation. Therefore, the current review aimed to summarize the related studies that addressed the molecular signature of the SDF-1/CXCR4 pathway and to explain how this axis is involved in normal events.

Indexed as

NeoplasmsReceptors, CXCR4Cell MovementChemokine CXCL12HumansNeovascularization, PathologicSignal TransductionChemokine CXCL12CXCR4 protein, humanReceptors, CXCR4ChemokinesCXCR4MigrationSDF-1Stem cells

Identifiers

PMID35067815
OpenAlexW4206914240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.