Evidence map›Paper›PMID 35067732›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Comparison of clinical practice guidelines on radiation dermatitis: a narrative review.

Samuel Finkelstein, Lauren Kanee, Tara Behroozian, Julie Ryan Wolf, Corina van den Hurk, Edward Chow, Pierluigi Bonomo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 13 pooled it
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 13 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Mepilex Lite dressing in the management of radiation dermatitis-a systematic review and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. MASCC clinical practice statement: Prevention and management of acute radiation dermatitis using topical corticosteroids.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Guideline
  3. Pooled it
  4. Guideline
  5. A critical review of randomized controlled trials on topical corticosteroids for the prevention of radiation dermatitis in breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Mepitel film for the prevention and treatment of acute radiation dermatitis in breast cancer: a systematic review and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  10. Prevention of radiation dermatitis with skin hygiene and washing: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  11. Topical non-steroidal agents for the prevention of radiation dermatitis: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  12. The effect of antiperspirant and deodorant use on acute radiation dermatitis in breast cancer patients during radiotherapy: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  13. Pooled it
  14. Trial
  15. Trial
  16. Article
  17. Critical reflections on pulsed electromagnetic field therapy for acute radiodermatitis: implications from Mohamed et al.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 5 countries.

Samuel FinkelsteinSackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lauren KaneeUniversity of Toronto, Toronto, ON, Canada.
Tara BehroozianUniversity of Waterloo, Waterloo, ON, Canada.
Julie Ryan WolfUniversity of Rochester Medical Centre, Rochester, NY, USA.
Corina van den HurkNetherlands Comprehensive Cancer Organisation, Utrecht, the Netherlands.
Edward ChowUniversity of Toronto, Toronto, ON, Canada. Edward.Chow@sunnybrook.ca.ORCID http://orcid.org/0000-0001-9808-5257
Pierluigi BonomoAzienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Azienda Ospedaliero-Universitaria Careggi · ITNetherlands Comprehensive Cancer Organisation · NLSunnybrook Health Science Centre · CATel Aviv University · ILUniversity of Rochester Medical Center · USUniversity of Toronto · CAUniversity of Waterloo · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRadiation dermatitis (RD) is a common side effect of radiation therapy (RT). While many different treatment strategies are currently used to address RD, there is a lack of consensus and RD prophylaxis and management guidelines have remained largely unchanged over the last 10 years. This review aims to formulate unambiguous supportive care interventions by comparing RD clinical practice guidelines published between 2010 and 2021 by several organizations: Multinational Association for Supportive Care in Cancer (MASCC), British Columbia Cancer Agency (BCCA), Cancer Care Manitoba (CCMB), Oncology Nursing Society (ONS), Society and College of Radiographers (SCoR), and International Society of Nurses in Cancer Care (ISNCC).

methodsAreas of agreement and discordance were assessed among the MASCC, BCCA, CCMB, ONS, SCoR, and ISNCC guidelines.

resultsTreatment recommendations across guidelines for acute RD and chronic RT-induced skin toxicities have been summarized. The strongest agreement among the guidelines exists for the use of topical corticosteroids, silver sulfadiazine, washing, and deodorant. All guidelines recommend the use of topical corticosteroids, and washing with water and soap is consistently supported. There is minimal consensus on an optimal dressing or barrier film for RD prophylaxis or management. MASCC weakly recommends prophylactic use of silver sulfadiazine to reduce RD, while BCCA, CCMB, and SCoR recommend its use upon signs of infection. MASCC and CCMB recommend the use of a long-pulsed dye laser to manage telangiectasia, a late effect of RT.

conclusionsGiven the extent of discordance among guideline recommendations, further research is recommended to establish optimal treatments for RD prophylaxis and management.

Indexed as

Dermatologic AgentsNeoplasmsRadiodermatitisAdrenal Cortex HormonesHumansPractice Guidelines as TopicSilver SulfadiazineAdrenal Cortex HormonesDermatologic AgentsSilver SulfadiazineChronic radiation-induced skin toxicitiesClinical practice guidelineRadiation dermatitisRadiation dermatitis managementRadiation dermatitis prophylaxisSkin care

Identifiers

PMID35067732
OpenAlexW4207073804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.