Evidence map›Paper›PMID 35066703›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2022

Contribution of objectively measured grating acuity by sweep visually evoked potentials to the diagnosis of unexplained visual loss.

Tarciana de Souza Soares, Adriana Berezovsky, Paula Yuri Sacai, Arthur Gustavo Fernandes, Daniel Martins Rocha, Carina Verna, Patrícia de Freitas Dotto, Sung Eun Song Watanabe, Solange Rios Salomão

Abstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tarciana de Souza SoaresLaboratório de Eletrofisiologia Visual Clínica, Departamento de Oftalmologia e Ciências Visuais Escola Paulista de Medicina, Universidade Federal de São Paulo-UNIFESP, R. Botucatu 816 CEP, São Paulo, SP, 04023-062, Brazil.
Adriana BerezovskyLaboratório de Eletrofisiologia Visual Clínica, Departamento de Oftalmologia e Ciências Visuais Escola Paulista de Medicina, Universidade Federal de São Paulo-UNIFESP, R. Botucatu 816 CEP, São Paulo, SP, 04023-062, Brazil.
Paula Yuri SacaiLaboratório de Eletrofisiologia Visual Clínica, Departamento de Oftalmologia e Ciências Visuais Escola Paulista de Medicina, Universidade Federal de São Paulo-UNIFESP, R. Botucatu 816 CEP, São Paulo, SP, 04023-062, Brazil.
Arthur Gustavo FernandesLaboratório de Eletrofisiologia Visual Clínica, Departamento de Oftalmologia e Ciências Visuais Escola Paulista de Medicina, Universidade Federal de São Paulo-UNIFESP, R. Botucatu 816 CEP, São Paulo, SP, 04023-062, Brazil.
Daniel Martins RochaLaboratório de Eletrofisiologia Visual Clínica, Departamento de Oftalmologia e Ciências Visuais Escola Paulista de Medicina, Universidade Federal de São Paulo-UNIFESP, R. Botucatu 816 CEP, São Paulo, SP, 04023-062, Brazil.
Carina VernaLaboratório de Eletrofisiologia Visual Clínica, Departamento de Oftalmologia e Ciências Visuais Escola Paulista de Medicina, Universidade Federal de São Paulo-UNIFESP, R. Botucatu 816 CEP, São Paulo, SP, 04023-062, Brazil.
Patrícia de Freitas DottoLaboratório de Eletrofisiologia Visual Clínica, Departamento de Oftalmologia e Ciências Visuais Escola Paulista de Medicina, Universidade Federal de São Paulo-UNIFESP, R. Botucatu 816 CEP, São Paulo, SP, 04023-062, Brazil.
Sung Eun Song WatanabeLaboratório de Eletrofisiologia Visual Clínica, Departamento de Oftalmologia e Ciências Visuais Escola Paulista de Medicina, Universidade Federal de São Paulo-UNIFESP, R. Botucatu 816 CEP, São Paulo, SP, 04023-062, Brazil.
Solange Rios SalomãoLaboratório de Eletrofisiologia Visual Clínica, Departamento de Oftalmologia e Ciências Visuais Escola Paulista de Medicina, Universidade Federal de São Paulo-UNIFESP, R. Botucatu 816 CEP, São Paulo, SP, 04023-062, Brazil. ssalomao@unifesp.br.ORCID http://orcid.org/0000-0002-3436-5599
Universidade Federal de São Paulo · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 01
6 · The paper itself

Abstract

purposeTo investigate the diagnostic contribution of grating visual acuity (GVA) measured by sweep pattern-reversal visually evoked potentials (SPRVEP) in unexplained visual loss (UVL).

methodsThis case-control study included adult patients under suspicion of UVL referred to SPRVEP and transient pattern-reversal visually evoked potentials (TPRVEP) testing. Optotype visual acuity (OVA) was measured by ETDRS 4-meter chart and GVA by SPRVEP. UVL patients were assigned into three distinctive categories, according to the presence of ocular disease, motivation, and electrophysiological evaluation, as follows: exaggerators, malingerers, and psychogenic. Healthy controls and patients with organic visual loss were also tested. Receiver operating characteristic (ROC) curve was constructed to evaluate the diagnostic performance of GVA and TPRVEP parameters.

resultsA total of 76 patients with UVL were analyzed: 60 (79.0%) exaggerators, 11 (14.4%) malingerers, and 5 (6.6%) psychogenic. Controls were 49 subjects evaluated for TPRVEP and 28 subjects for SPRVEP. There were 13 patients with organic visual loss enrolled. Mean difference between OVA and GVA was 1.19±0.67 (median=0.84; 95% CI: 1.04 to 1.34) in UVL and 0.14 ±0.09 (median= 0.14; 95% CI: 0.08 to 0.20) in organic visual loss. The area under the ROC curve (AUC) of GVA to distinguish UVL from healthy controls was 0.998 with a cutoff of 0.09 logMAR showing specificity of 100% and sensitivity of 96.0%.

conclusionsGVA measured by SPRVEP had good diagnostic validity to discriminate patients with unexplained visual loss from healthy controls and patients with organic visual loss, demonstrating its contribution to the diagnosis of this condition.

Indexed as

Evoked Potentials, VisualVision DisordersAdultBlindnessCase-Control StudiesEvoked PotentialsHumansVisual AcuityAdultsMalingeringSweep VEPUnexplained visual lossVisual acuityVisual evoked potentials

Identifiers

PMID35066703
OpenAlexW4207024508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.