Evidence map›Paper›PMID 35066672›Full record

ArticleMikrochimica acta2022

Carbon quantum dots-Annexin V probe: photoinduced electron transfer mechanism, phosphatidylserine detection, and apoptotic cell imaging.

Mohamad Mahani, Parisa Karimi-Mazidi, Faeze Khakbaz, Masoud Torkzadeh-Mahani

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Article in Mikrochimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mohamad MahaniDepartment of Chemistry, Faculty of Chemistry and Chemical Engineering, Graduate University of Advanced Technology, 7631818356, Kerman, Iran. mohmahani@gmail.com.ORCID http://orcid.org/0000-0001-5258-8561
Parisa Karimi-MazidiDepartment of Chemistry, Faculty of Chemistry and Chemical Engineering, Graduate University of Advanced Technology, 7631818356, Kerman, Iran.
Faeze KhakbazDepartment of Nano Chemistry, Faculty of Chemistry, Shahid Bahonar University, Kerman, Iran.
Masoud Torkzadeh-MahaniDepartment of Biotechnology, Institute of Science, High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran.
Graduate University of Advanced Technology · IRShahid Bahonar University of Kerman · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An annexin V-based probe is designed and fabricated using carbon quantum dot as highly stable and biocompatible fluorescent crystals for real-time fluorescence imaging of apoptotic cells. Carbon quantum dots were synthesized, characterized, and conjugated to annexin V. The fluorescence of CQDs at 450 nm (excitation at 350 nm) is quenched due to the photoinduced electron transfer between "carbon quantum dots" and two amino acids (tyrosine and tryptophan) in the annexin structure as quencher. The probe shows very strong and bright fluorescence emission in the presence of phosphatidylserine on the outer layer of the apoptotic cell membrane. It was shown that using fluorescence spectroscopy, the probe can be applied to sensitive phosphatidylserine determination and using fluorescence microscopy, it is possible to monitor cell apoptosis in real time.

Indexed as

Amino AcidsAnnexin A5ApoptosisCarbonCell LineCell SurvivalElectron TransportHumansMCF-7 CellsPhosphatidylserinesQuantum DotsSingle-Cell AnalysisAmino AcidsAnnexin A5CarbonPhosphatidylserinesAnnexin-VApoptotic cell imagingCarbon quantum dotsFluorescence spectroscopyPhosphatidylserinePhotoinduced electron transfer

Identifiers

PMID35066672
OpenAlexW4207031642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.