Evidence map›Paper›PMID 35066630›Full record

ArticleZeitschrift fur Rheumatologie2023

[Pain reduction by radiosynoviorthesis in rheumatism-induced synovitis of the elbow : Results of a retrospective multicenter data analysis].

Lutz S Freudenberg, Xenofon Baraliakos, Willm Uwe Kampen, Marika Vereb, Manfred Fischer, Gregor Toenshoff, Barbara Boddenberg-Pätzold, Norbert Czech, Rigobert Klett

Abstract readMulticenter StudyEnglish Abstract
PubMed Publisher
In one paragraph

Article in Zeitschrift fur Rheumatologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Lutz S FreudenbergZRN Rheinland und ZRN MVZ GmbH, Überseite 88, 41352, Korschenbroich, Deutschland. l.freudenberg@zrn-info.de.ORCID http://orcid.org/0000-0002-9362-1222
Xenofon BaraliakosRheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Claudiusstr. 45, 44649, Herne, Deutschland.
Willm Uwe KampenExzellenznetzRSO e. V., Langgöns, Deutschland, 53428.
Marika VerebPraxis für Radiologie, Nuklearmedizin und Strahlentherapie, Fr.-Ebert-Str. 50, 34117, Kassel, Deutschland.
Manfred FischerExzellenznetzRSO e. V., Langgöns, Deutschland, 53428.
Gregor ToenshoffExzellenznetzRSO e. V., Langgöns, Deutschland, 53428.
Barbara Boddenberg-PätzoldExzellenznetzRSO e. V., Langgöns, Deutschland, 53428.
Norbert CzechExzellenznetzRSO e. V., Langgöns, Deutschland, 53428.
Rigobert KlettExzellenznetzRSO e. V., Langgöns, Deutschland, 53428.
Klinik und Poliklinik für Nuklearmedizin · DEKrankenhaus St. Joseph-Stift Bremen · DERheumazentrum Ruhrgebiet · DESpital Linth · CHZentrum für Pathologie und Zytodiagnostik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiosynoviorthesis (RSO) is a nuclear medical local treatment modality for inflammatory joint diseases. It is indicated in patients with rheumatoid arthritis (RA) in joints with persistent synovitis despite adequate pharmacotherapy. Arthritis of the elbow joint occurs in up to 2/3 of patients with RA. Intra-articular radiotherapy using the beta emitter [

objectiveThe degree of pain alleviation by RSO was analyzed in patients with rheumatoid cubital arthritis, treated in several nuclear medical practices specialized in RSO. MATERIAL AND

methodsThe subjective pain intensity before and after RSO was documented in a total of 107 patients with rheumatic cubital arthritis using a 10-step numeric rating scale (NRS). A difference of ≥ -2 is rated as a significant improvement. Follow-up examinations were done after a mean interval of 14 months after RSO (at least 3 months, maximum 50 months).

resultsThe mean NRS value was 7.3 ± 2.1 before RSO and 2.8 ± 2.2 after RSO. A significant pain alleviation was seen in 78.5% of all patients treated. The subgroup analysis also showed a significant improvement in the pain symptoms in all groups depending on the time interval between the RSO and the control examination. A significant pain progression was not observed. The degree of pain relief was independent of the time of follow-up.

conclusionUsing RSO for local treatment of rheumatoid cubital arthritis leads to a significant and long-lasting pain relief in more than ¾ of the treated patients.

Indexed as

Arthritis, RheumatoidCollagen DiseasesElbow JointRheumatic DiseasesSynovitisElbowHumansPainRadioisotopesTreatment OutcomeRadioisotopes[186Re] Rhenium sulfideNuclear medicinePain treatmentRheumatoid arthritisRSO

Identifiers

PMID35066630
OpenAlexW4206982411

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.