Evidence map›Paper›PMID 35066611›Full record

ArticlePflugers Archiv : European journal of physiology2022

Roles of stretch-activated channels and NADPH oxidase 2 in the induction of twitch contraction by muscle stretching in rat ventricular muscle.

Haruka Sato, Tsuyoshi Nagano, Wakako Satoh, Kazunori Kumasaka, Chiyohiko Shindoh, Masahito Miura

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Mitochondrial connexin43 and mitochondrial KPflugers Archiv : European journal of physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Haruka SatoDepartment of Clinical Physiology, Health Science, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan.
Tsuyoshi NaganoDepartment of Clinical Physiology, Health Science, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan.
Wakako SatohDepartment of Clinical Physiology, Health Science, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan.
Kazunori KumasakaDepartment of Clinical Physiology, Health Science, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan.
Chiyohiko ShindohDepartment of Clinical Physiology, Health Science, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan.
Masahito MiuraDepartment of Clinical Physiology, Health Science, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan. mmiura@med.tohoku.ac.jp.ORCID 0000-0003-0313-1308
Tohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechano-electric feedback means that muscle stretching causes depolarization of membrane potential. We investigated whether muscle stretching induces action potential and twitch contraction with a threshold of sarcomere length (SL) and what roles stretch-activated channels (SACs) and stretch-activated NADPH oxidase (X-ROS signaling) play in the induction. Trabeculae were obtained from the right ventricles of rat hearts. Force, SL, and [Ca

Indexed as

Heart VentriclesMyocardial ContractionAnimalsArrhythmias, CardiacCalciumMuscle ContractionNADPH Oxidase 2RatsReactive Oxygen SpeciesSarcomeresCalciumNADPH Oxidase 2Reactive Oxygen SpeciesForceMuscle stretchingNADPH oxidase 2Stretch-activated channels

Identifiers

PMID35066611
OpenAlexW4207066195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.