ReviewInternational journal for parasitology. Drugs and drug resistance2022
Focused review: The role of drug combinations for the control of coccidiosis in commercially reared chickens.
Review in International journal for parasitology. Drugs and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review and Meta-Analysis of the Efficacy of Biosecurity in Disease Prevention and Control in Livestock Farms in Africa.Transboundary and emerging diseases · 2024Pooled it
- A century of "anticoccidial drugs": bibliometric analysis.Frontiers in veterinary science · 2023Pooled it
- Integrated Phytochemical, Computational and In Vitro Evaluation of the Oocysticidal Activity of Pleurotus ostreatus Extract Against Cryptosporidium parvum.Cell biochemistry and biophysics · 2026Article
- First anticoccidial sensitivity test applied to Eimeria lata: evidence of reduced sensitivity to nicarbazin in a Brazilian field isolate.Veterinary research communications · 2026Article
- Stability-Indicating HPLC Method for Simultaneous Determination of Sulfadimethoxine and Ormetoprim in an Oral Solution.ACS omega · 2026Article
- Nanotechnology-Enabled Approaches in Poultry Coccidiosis Management: Advances, Challenges, and Future Perspectives.Poultry science · 2026Review
- In Vitro and In Vivo Study of Green-Synthesized Zinc Oxide Nanoparticles as a Novel Anticoccidial Agent.Acta parasitologica · 2026Article
- A Tetravalent Recombinant Subunit Vaccine Provides Protection Against Mixed Challenges with FourAnimals : an open access journal from MDPI · 2026Article
- Molecular characterization of Eimeria necatrix surface antigen SAG8 and SAG36 genes and their immunoprotective efficacy in chicken.BMC veterinary research · 2026Article
- Increased caecal Intestinimonas abundance inhibits E. tenella gametogenesis via EtGFAT regulation and alleviates infection through immunity.Microbiome · 2026Article
- UnderstandingFrontiers in cellular and infection microbiology · 2026Review
- Anticoccidial Resistance inVeterinary medicine international · 2026Article
- Novel organoids andParasitology · 2025Review
- Saccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative status.BMC veterinary research · 2025Article
- Preventive and therapeutic efficacy of a pyrazole-modified chitosan Schiff base-iron nanocomposite againstVeterinary world · 2025Article
- Effects of probiotics and amprolium on performance, lesion scores, oocyst shedding, and histopathological changes inVeterinary world · 2025Article
- Prevalence and anticoccidial drug sensitivity ofVeterinary world · 2025Article
- Genetic manipulation for the non-model protozoaniScience · 2025Review
- Astragalus polysaccharide mitigates Eimeria tenella-induced damage in laying chicks by modulating immunity, inflammation, and intestine barrier.Journal of animal science · 2025Article
- Comparative analysis of pathogenicity and anticoccidial resistance of field-isolatedFrontiers in veterinary science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A survey of drug combinations employed by the poultry industry indicates that they have played an important role in the control of coccidiosis in chickens. The mode of action of their component drugs is described. Advantages that accrue from their use may include a reduction in potential toxicity, a broadening of their spectrum of activity against different species of Eimeria, activity against different stages of the life cycle, and improved efficacy due to synergism between component drugs. Integration of management procedures involving rotation of drug combinations with vaccination is desirable because this has been shown to result in a restoration of drug sensitivity where drug resistance is present and could contribute to the sustainable control of coccidiosis. Threats to the future use of the most widely used combinations, those that include ionophores, stem from the recent desire to eliminate antibiotics from poultry feeds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.