Evidence map›Paper›PMID 35066393›Full record

ArticleMedical image analysis2022

Automated identification of pulmonary arteries and veins depicted in non-contrast chest CT scans.

Jiantao Pu, Joseph K Leader, Jacob Sechrist, Cameron A Beeche, Jatin P Singh, Iclal K Ocak, Michael G Risbano

Abstract read
In one paragraph

Article in Medical image analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  17. CT-Derived Features as Predictors of Clot Burden and Resolution.Bioengineering (Basel, Switzerland) · 2024
    Article
  18. Article
  19. Article
  20. A new segment method for pulmonary artery and vein.Health information science and systems · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiantao PuDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, United States of America; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, United States of America. Electronic address: puj@upmc.edu.
Joseph K LeaderDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, United States of America.
Jacob SechristDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, United States of America.
Cameron A BeecheDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, United States of America.
Jatin P SinghDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, United States of America.
Iclal K OcakDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, United States of America.
Michael G RisbanoDivision of Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, United States of America.

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
Macro-vasculature: A Novel Image Biomarker of Lung CancerR01CA237277 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PU, JIANTAO · 2020 to 2024
$2.8M
NCI NIH HHS P30 CA047904NCI NIH HHS R01 CA237277
6 · The paper itself

Abstract

We present a novel integrative computerized solution to automatically identify and differentiate pulmonary arteries and veins depicted on chest computed tomography (CT) without iodinated contrast agents. We first identified the central extrapulmonary arteries and veins using a convolutional neural network (CNN) model. Then, a computational differential geometry method was used to automatically identify the tubular-like structures in the lungs with high densities, which we believe are the intrapulmonary vessels. Beginning with the extrapulmonary arteries and veins, we progressively traced the intrapulmonary vessels by following their skeletons and differentiated them into arteries and veins. Instead of manually labeling the numerous arteries and veins in the lungs for machine learning, this integrative strategy limits the manual effort only to the large extrapulmonary vessels. We used a dataset consisting of 120 chest CT scans acquired on different subjects using various protocols to develop, train, and test the algorithms. Our experiments on an independent test set (n = 15) showed promising performance. The computer algorithm achieved a sensitivity of ∼98% in labeling the pulmonary artery and vein branches when compared with a human expert's results, demonstrating the feasibility of our computerized solution in pulmonary artery/vein labeling.

Indexed as

Pulmonary ArteryTomography, X-Ray ComputedAlgorithmsHumansNeural Networks, ComputerThoraxArteryComputed tomographyDeep learningDifferential geometryVein

Identifiers

PMID35066393
PMCPMC8901546

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.