Evidence map›Paper›PMID 35065975›Full record

Trial reportPreventive medicine2022

Where you live matters: Township neighborhood factors important to resilience among south African children from birth to 5 years of age.

Joan Christodoulou, Mary Jane Rotheram-Borus, Panteha Hayati Rezvan, W Scott Comulada, Jackie Stewart, Ellen Almirol, Mark Tomlinson

Registry-linked trialAbstract readRandomized Controlled TrialClinical Trial, Phase III
In one paragraph

Trial report in Preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00996528 (Neighborhood Alcohol & HIV Prevention in South African Townships), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00996528 phase3unknown statusnot on this map

Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)

TypeinterventionalSponsorUniversity of California, Los AngelesRan2007 to 2025Enrolled1,239ConditionsFetal Alcohol Syndrome, HIV, Nutrition DisordersArmsPhilani Intervention Program
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joan ChristodoulouPalo Alto University, USA. Electronic address: jchristodoulou@paloaltou.edu.
Mary Jane Rotheram-BorusDepartment of Psychiatry & Biobehavioral Sciences, Semel Institute, University of California, Los Angeles, CA, USA.
Panteha Hayati RezvanDepartment of Psychiatry & Biobehavioral Sciences, Semel Institute, University of California, Los Angeles, CA, USA.
W Scott ComuladaDepartment of Psychiatry & Biobehavioral Sciences, Semel Institute, University of California, Los Angeles, CA, USA.
Jackie StewartDepartment of Global Health, Stellenbosch University, Stellenbosch, South Africa.
Ellen AlmirolDepartment of Psychiatry & Biobehavioral Sciences, Semel Institute, University of California, Los Angeles, CA, USA.
Mark TomlinsonDepartment of Global Health, Stellenbosch University, Stellenbosch, South Africa.

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KITCHEN, SCOTT G · 1991 to 2018
$39.9M
Neighborhood Alcohol & HIV Prevention in South African TownshipsR01AA017104 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2007 to 2011
$3.8M
Post-doctoral HIV Research Training Program for HIV Combination PreventionT32MH109205 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2016 to 2020
$2.3M
NIAAA NIH HHS R01 AA017104NIAID NIH HHS P30 AI028697NIMH NIH HHS P30 MH058107NIMH NIH HHS T32 MH109205
6 · The paper itself

Abstract

objectiveThis is a secondary analysis examining neighborhood factors predicting high rates of child resilience in South African Township neighborhoods.

methodsA population cohort of South African pregnant women (98%; n = 1238), were recruited and assessed across five years with high follow-up rates (83-96%). Resilient children were identified based on consistently meeting global standards for growth, cognitive functioning, and behavior. Community infrastructure, maternal risks, and caretaking behaviors were examined based on neighborhood as predictors of childhood resilience.

resultsThe rate of resilient children varied significantly by neighborhood (9.5% to 27%). Mothers living in high prevalence neighborhoods (HPN) compared to low prevalence neighborhoods (LPN) were older and more likely be living with three or more people in formal housing with access to water and electricity. In the HPN, resilient children had more food security and were less likely to have mothers with depressed mood. Migration to rural areas occurred more frequently among resilient compared to non-resilient children in the HPN.

conclusionThis study applies a novel measure of resilience that is multidimensional and longitudinally defined. Living in formal housing with consistent access to food was associated with resilience. Migration to rural areas among families living in HPN suggests that rural areas could be protective.

trial registrationClinicalTrials.gov registration #NCT00996528.

Indexed as

Residence CharacteristicsResilience, PsychologicalChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornMaleMothersPregnancySouth AfricaChild developmentLow middle income countriesMaternal and child healthResilienceSouth Africa

Identifiers

PMID35065975
PMCPMC11495511

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.