ArticleCell2022
A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 88 papers.
0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
14.4field-weighted citation impact, top 1% of its field
What it found
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Who cites it
88 citing papers in PubMed, 151 citations in OpenAlex.
- Estrogen/Esr2b signaling-dependent, female-biased expression of a neuropeptide Y gene in the medaka brain.Journal of neuroendocrinology · 2026Article
- A male-biased hypothalamic circuit modulates postmating sleep suppression in mice.Science advances · 2026Article
- Proenkephalin neurons in the adBNST mitigate stress-induced anxiety and estrous cycle disruption in female mice.Neurobiology of stress · 2026Article
- Hypothalamic representation of aggressiveness across mouse strains.Nature communications · 2026Article
- Standardized chronic restraint stress protocols reveal dynamic evolution of behavioral adaptations in male mice: implications for translational neuroscience.Molecular psychiatry · 2026Article
- Spatial transcriptomics reveals distinct cell type dynamics following opioid dependence in female mice with the common human μ-opioid receptor variant Oprm1 A118G.Nature communications · 2026Article
- A Distinct Subpopulation of Extended Amygdala Neurons Drives Food Intake.Biological psychiatry global open science · 2026Article
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- The hormonal and neural control of maternal aggression.Current opinion in neurobiology · 2026Review
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- From identity to function: unveiling the cellular complexity of hypothalamic feeding circuits.Reviews in endocrine & metabolic disorders · 2026Review
- Nmur1 and Cckar fail to support functional genetic access in adult dopamine neurons and challenge GPCR atlas assignments.bioRxiv : the preprint server for biology · 2026Article
- Advancing insights into the neuroendocrine basis of socio-sexual interactions in mammals.Endocrinology · 2026Review
- Regulation of physical activity and energy expenditure through Phf6 in the medial preoptic area.Nature communications · 2026Article
- The neural control of infanticide and parental behaviors in male mice.bioRxiv : the preprint server for biology · 2026Article
- Hormonal regulation of cochlear gene expression: effects of the estrous cycle, ovariectomy, and estradiol treatment.Biology of sex differences · 2026Article
- Single-cell map of the female brain across reproductive transitions.bioRxiv : the preprint server for biology · 2026Article
- Spatially resolved molecular sex differences at single-cell resolution in the adult human ventromedial and arcuate hypothalamus.Cell reports · 2026Article
- A sexually dimorphic neuronal cluster in the mouse medial amygdala responds to male sexual status.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Integrative transcriptome-wide association analyses reveal PRKCG-linked GABAergic dysfunction in Fragile X-associated tremor/ataxia syndrome.Nature communications · 2026Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
15 authors at 4 institutions in 1 country.
Joseph R KnoedlerDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Sayaka InoueDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Daniel W BaylessDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Taehong YangDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Adarsh TantryDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Chung-Ha DavisNeurosciences Graduate Program, Stanford University, Stanford, CA 94305, USA.
Nicole Y LeungDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Srinivas ParthasarathyAccent Therapeutics, 65 Hayden Avenue, Lexington, MA 02421, USA.
Grace WangDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Maricruz AlvaradoDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Abbas H RizviZuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA.
Lief E FennoDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
Charu RamakrishnanCNC Program, Stanford University, Stanford, CA 94305, USA.
Karl DeisserothDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Nirao M ShahDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA; Department of Neurobiology, Stanford University, Stanford, CA 94305, USA. Electronic address: nirao@stanford.edu.
Stanford University · USAccent Therapeutics (United States) · USColumbia University · USStanford Medicine · US
Funding
Characterization of Sexual Dimorphism in the BrainR01NS049488 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nirao Mahesh Shah · 2005 to 2026
$8.7MMicrocircuit, cellular and molecular dissection of impaired hippocampal function in a mouse model of the 22q11.2 deletionR01MH124047 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOGOS, JOSEPH A, LOSONCZY, ATTILA · 2020 to 2024
$3.8MInterrogating genome folding trajectories in health and diseaseU01DA052783 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOMVARDAS, STAVROS · 2020 to 2024
$3.1MConnectivity, activity, and function of a hypothalamic pathway in female social behaviorsR01HD104565 · NICHD · STANFORD UNIVERSITY · PI DING, JUN, SHAH, NIRAO MAHESH · 2021 to 2025
$2.5MFour Laser, 18 Color Cell Sorter in the SSFFS10RR025518 · NCRR · STANFORD UNIVERSITY · PI HERZENBERG, LEONARD A · 2009 to 2009
$500kLarge-Scale Mapping of Striatal Dynamics during Perceptual Decision MakingF32MH123047 · NIMH · PRINCETON UNIVERSITY · PI BONDY, ADRIAN GOPNIK · 2021 to 2023
$228kIdentifying mediators of sex hormone uptake and signalingF32MH125593 · NIMH · STANFORD UNIVERSITY · PI LEUNG, NICOLE YISHI · 2020 to 2022
$114kNCRR NIH HHS S10 RR025518NICHD NIH HHS R01 HD104565NIDA NIH HHS U01 DA052783NIMH NIH HHS F32 MH123047NIMH NIH HHS F32 MH125593NIMH NIH HHS R01 MH124047NINDS NIH HHS R01 NS049488
Abstract
Sex hormones exert a profound influence on gendered behaviors. How individual sex hormone-responsive neuronal populations regulate diverse sex-typical behaviors is unclear. We performed orthogonal, genetically targeted sequencing of four estrogen receptor 1-expressing (Esr1
Indexed as
Gene Expression RegulationSex CharacteristicsAggressionAnimalsAromataseAutistic DisorderEstrogen Receptor alphaEstrous CycleFemaleGene Expression ProfilingHEK293 CellsHumansMaleMiceMice, Inbred BALB CMice, Inbred C57BLAromataseEstrogen Receptor alphaaggressiondeep sequencingestrous cyclematernal behaviormatingmenstrual cyclesex differencessocial behaviorssynaptic plasticitytranscriptomically defined cell types
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.