Evidence map›Paper›PMID 35065668›Full record

ArticleArthritis research & therapy2022

"The medications are the decision-makers…" Making reproductive and medication use decisions among female patients with rheumatoid arthritis: a constructivist grounded theory.

Nevena Rebić, Sarah Munro, Ria Garg, Glen Hazlewood, Neda Amiri, Corisande Baldwin, Stephanie Ensworth, Laurie Proulx, Mary A De Vera

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arthritis research & therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Nevena RebićFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Sarah MunroCentre for Health Evaluation and Outcome Sciences, Vancouver, BC, Canada.
Ria GargFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Glen HazlewoodArthritis Research Centre of Canada, Vancouver, BC, Canada.
Neda AmiriArthritis Research Centre of Canada, Vancouver, BC, Canada.
Corisande BaldwinFaculty of Medicine, Department of Medicine, Division of Rheumatology, University of British Columbia, Vancouver, BC, Canada.
Stephanie EnsworthFaculty of Medicine, Department of Medicine, Division of Rheumatology, University of British Columbia, Vancouver, BC, Canada.
Laurie ProulxCanadian Arthritis Patient Alliance, Ottawa, ON, Canada.
Mary A De VeraFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada. mdevera@mail.ubc.ca.ORCID 0000-0002-2205-2683
University of British Columbia · CACanadian Arthritis Patient Alliance · CAUniversity of Calgary · CA

Funding

CIHR
6 · The paper itself

Abstract

objectiveTo examine how female patients with RA form decisions about having children, pregnancy, and medication use.

methodsWe employed a constructivist grounded theory design and recruited female participants who are 18 years or older, have a rheumatologist-confirmed RA diagnosis, live in Canada, and are able to communicate in English or French. We collected data through semi-structured individual and focus group interviews using telephone or video conferencing technology. Data collection and analysis were iterative, employed theoretical sampling, reflexive journaling, and peer debriefing, and culminated in a theoretical model.

resultsWe recruited 21 participants with a mean age of 34 years and median 10 years since RA diagnosis. Overall, 33% had never been pregnant, 57% had previously been pregnant, and 10% were pregnant at the time of interview. Of those who had experienced pregnancy, 64% had at least one pregnancy while diagnosed with RA and of those, 56% used DMARD(s) during a pregnancy. We constructed a patient-centred framework depicting the dynamic relationships between 4 decision-making processes-(1) using medications, (2) having children, (3) planning pregnancy, and (4) parenting-and the substantial impact of healthcare providers on patients' experiences making these decisions. These processes were further influenced by participants' intersecting identities and contextual factors, particularly attitudes towards health and medications, disease onset and severity, familial support system, and experiences interacting with the healthcare system.

conclusionOur framework provides insight into how patients make reproductive decisions in the context of managing RA and the opportunities for providers to support them at each decision-making process. A patient-centred care approach is suggested to support female patients with RA in making reproductive and medication choices aligning with their individual desires, needs, and values.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidAdultChildDecision MakingFemaleGrounded TheoryHumansPeer GroupPregnancyAntirheumatic AgentsMedication usePregnancyQualitative studyRheumatoid arthritis

Identifiers

PMID35065668
PMCPMC8783434
OpenAlexW4207039504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.