Evidence map›Paper›PMID 35065663›Full record

ArticleEuropean journal of medical research2022

Incidence and risk factors of in-stent restenosis after percutaneous coronary intervention in patients from southern China.

Mingrui Li, Jingyuan Hou, Xiaodong Gu, Ruiqiang Weng, Zhixiong Zhong, Sudong Liu

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  6. Observational
  7. Review
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  10. Predictive Scoring Model for In-Stent Restenosis Risk in Coronary Artery Disease Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  11. Article
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  17. Intrastent Restenosis: A Comprehensive Review.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mingrui Li *Faculty of Graduate Studies, Guangdong Medical University, Zhanjiang, 524000, People's Republic of China.
Jingyuan Hou *Research Experimental Center, Meizhou People's Hospital (Huangtang Hospital), Meizhou, 514031, People's Republic of China.
Xiaodong GuResearch Experimental Center, Meizhou People's Hospital (Huangtang Hospital), Meizhou, 514031, People's Republic of China.
Ruiqiang WengResearch Experimental Center, Meizhou People's Hospital (Huangtang Hospital), Meizhou, 514031, People's Republic of China.
Zhixiong ZhongCenter for Cardiovascular Diseases, Meizhou People's Hospital (Huangtang Hospital), Meizhou, 514031, People's Republic of China. zhongzhixiong@mzrmyy.com.
Sudong LiuResearch Experimental Center, Meizhou People's Hospital (Huangtang Hospital), Meizhou, 514031, People's Republic of China. vanguard_1987@163.com.
Meizhou City People's Hospital · CNGuangdong Medical College · CNThermo Fisher Scientific (China) · CN

Funding

Guangdong Provincial Key Laboratory of Precision Medicine and Clinical Translational Research of Hakka Population 2018B030322003National Natural Science Foundation for Young Scientists of China 82000410National Natural Science Foundation for Young Scientists of China 82002216Scientific Research and Cultivation Project of Meizhou People's Hospital PY-A2019002the Science and Technology Program of Meizhou 2019B0202001
6 · The paper itself

Abstract

backgroundIn-stent restenosis (ISR) remains a challenge for coronary artery disease (CAD) patients who undergo percutaneous coronary intervention (PCI) with stents, and risk factors for ISR are controversial. This study aimed to investigate the incidence and risk factors of ISR in patients from southern China.

methodsIn this retrospective study, patients diagnosed as acute coronary syndromes (ACS) and underwent successful PCI with drug-eluting stent (DES) and conducted a follow-up coronary angiography in Center for Cardiovascular Diseases of Meizhou People's Hospital at the period of January 1st, 2016 to January 1st, 2021 were included for analysis. The clinical and angiographic factors were compared between patients in ISR ( +) and ISR (-) groups. The association between variables and ISR was evaluated by multivariate logistic regression model.

resultA total of 341 ACS patients who had been installed at least 1 stent were included in this study. The follow-up time was 34.2 ± 17.2 months. During the follow-up period, 62 (18.2%) patients experienced ISR, and the average time for ISR was 32.8 months; the incidence of ISR for left main coronary artery, left anterior descending coronary artery, left circumflex artery coronary artery and right coronary artery were 6.7%, 20.9%, 19.4% and 14.4%, respectively; left ventricular ejection fraction (LVEF), stent number, stent type, statin therapy, antiplatelet therapy were significantly different between patients in ISR ( +) and ISR (-) group. Multivariate logistic analysis suggested that LVEF and stent number were significantly correlated with ISR.

conclusionOur study revealed the incidence and risk factors of ISR in patients from southern China. Our data suggested that LVEF and stent number were independent risk factors associated with ISR.

Indexed as

ChinaCoronary AngiographyCoronary RestenosisCoronary VesselsDrug-Eluting StentsGraft Occlusion, VascularHumansIncidencePercutaneous Coronary InterventionRetrospective StudiesRisk AssessmentRisk FactorsDrug-eluting stent (DES)In-stent restenosis (ISR)Percutaneous coronary intervention (PCI)Risk factor

Identifiers

PMID35065663
PMCPMC8783476
OpenAlexW4206974075

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.