Evidence map›Paper›PMID 35064846›Full record

ArticleThe international journal of cardiovascular imaging2022

Changes in left atrial appendage orifice following percutaneous left atrial appendage closure using three-dimensional echocardiography.

Xochitl A Ortiz-Leon, Edith L Posada-Martinez, Alda Bregasi, Wanwen Chen, Ian Crandall, Jason Pereira, Kamil F Faridi, Joseph G Akar, Ben A Lin, Robert L McNamara and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xochitl A Ortiz-LeonLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Edith L Posada-MartinezLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Alda BregasiLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Wanwen ChenLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Ian CrandallLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Jason PereiraLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Kamil F FaridiLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Joseph G AkarLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Ben A LinLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Robert L McNamaraLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
James V FreemanLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Jeptha CurtisLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Jose A Arias-GodinezLaboratory of Echocardiography, National Institute of Cardiology, Juan Badiano 1, Belisario Domínguez Secc. 16, 14080, Mexico City, Mexico.
Lissa SugengLaboratory of Echocardiography, Yale New Haven Hospital, Cardiovascular Division, Yale School of Medicine, 20 York Street, New Haven, CT, 06510, USA. lissa.sugeng@yale.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Percutaneous left atrial appendage (LAA) occlusion is increasingly performed in patients with atrial fibrillation and long-term contraindications for anticoagulation. Our aim was to evaluate the effects of LAA occlusion with the Watchman device on the geometry of the LAA orifice and assess its impact on the adjacent left upper pulmonary vein (LUPV) hemodynamics. We included 50 patients who underwent percutaneous LAA occlusion with the Watchman device and had acceptable three-dimensional transesophageal echocardiography images of LAA pre- and post-device placement. We measured offline the LAA orifice diameters in the long axis, and the minimum and maximum diameters, circumference, and area in the short axis view. Eccentricity index was calculated as maximum/minimum diameter ratio. The LUPV peak S and D velocities pre- and post-procedure were also measured. Patients were elderly (mean age 76 ± 8 years), 30 (60%) were men. There was a significant increase of all LAA orifice dimensions following LAA occlusion: diameter 1 (pre-device 18.1 ± 3.2 vs. post-device 21.5 ± 3.4 mm, p < 0.001), diameter 2 (20.6 ± 3.9 vs. 22.1 ± 3.6 mm, p < 0.001), minimum diameter (17.6 ± 3.1 vs. 21.3 ± 3.4 mm, p < 0.001), maximum diameter (21.5 ± 3.9 vs. 22.4 ± 3.6 mm, p = 0.022), circumference (63.6 ± 10.7 vs. 69.6 ± 10.5 mm, p < 0.001), and area (3.1 ± 1.1 vs. 3.9 ± 1.2 cm

Indexed as

Atrial fibrillationLeft atrial appendage occlusionThree-dimensional echocardiographyWatchman device

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.