ArticleHuman brain mapping2022
Differentiating distinct and converging neural correlates of types of systemic environmental exposures.
Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Neighborhood Deprivation and Adolescent Mental Health: The Protective Role of School Staffing Patterns.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Geographic Measures of Early Life-Course Social Exposome in the Evaluation of Structural Neuroanatomy: A Scoping Review.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Review
- Associations of neighborhood threat and deprivation with psychopathology: Uncovering neural mechanisms.Development and psychopathology · 2025Article
- How does the macroenvironment influence brain and behaviour-a review of current status and future perspectives.Molecular psychiatry · 2024Review
- Longitudinal study of peer victimization, social support, and mental health during early adolescence.Psychological medicine · 2024Article
- How does the macroenvironment influence brain and behaviour - a review of current status and future perspectives.medRxiv : the preprint server for health sciences · 2023Article
- Review of Major Social Determinants of Health in Schizophrenia-Spectrum Disorders: II. Assessments.Schizophrenia bulletin · 2023Article
- The Critical Roles of Early Development, Stress, and Environment in the Course of Psychosis.Annual review of developmental psychology · 2022Article
- Differentiating distinct and converging neural correlates of types of systemic environmental exposures.Human brain mapping · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Systemic environmental disadvantage relates to a host of health and functional outcomes. Specific structural factors have seldom been linked to neural structure, however, clouding understanding of putative mechanisms. Examining relations during childhood/preadolescence, a dynamic period of neurodevelopment, could aid bridge this gap. A total of 10,213 youth were recruited from the Adolescent Brain and Cognitive Development study. Self-report and objective measures (Census and Federal bureau of investigation metrics extracted using geocoding) of environmental exposures were used, including stimulation indexing lack of safety and high attentional demands, discrepancy indexing social exclusion/lack of belonging, and deprivation indexing lack of environmental enrichment. Environmental measures were related to cortical thickness, surface area, and subcortical volume regions, controlling for other environmental exposures and accounting for other brain regions. Self-report (|β| = .04-.09) and objective (|β| = .02-.06) environmental domains related to area/thickness in overlapping (e.g., insula, caudal anterior cingulate), and unique regions (e.g., for discrepancy, rostral anterior and isthmus cingulate, implicated in socioemotional functions; for stimulation, precuneus, critical for cue reactivity and integration of environmental cues; and for deprivation, superior frontal, integral to executive functioning). For stimulation and discrepancy exposures, self-report and objective measures showed similarities in correlate regions, while deprivation exposures evidenced distinct correlates for self-report and objective measures. Results represent a necessary step toward broader work aimed at establishing mechanisms and correlates of structural disadvantage, highlighting the relevance of going beyond aggregate models by considering types of environmental factors, and the need to incorporate both subjective and objective measurements in these efforts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.