Evidence map›Paper›PMID 35064519›Full record

ArticleJournal of nephrology2022

Association between expanded criteria for living kidney donors and renal biopsy findings.

Shunsuke Goto, Hideyo Oguchi, Ken Sakai, Tetsuo Mikami, Daisuke Ichikawa, Masahiko Yazawa, Junki Koike, Kengo Furuichi, Masahiko Kawabata, Hitoshi Yokoyama and 3 more

Erratum issuedAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Shunsuke GotoDivision of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. sgoto@med.kobe-u.ac.jp.
Hideyo OguchiDepartment of Nephrology, Faculty of Medicine, Toho University, Tokyo, Japan.
Ken SakaiDepartment of Nephrology, Faculty of Medicine, Toho University, Tokyo, Japan.
Tetsuo MikamiDepartment of Pathology, Faculty of Medicine, Toho University, Tokyo, Japan.
Daisuke IchikawaDivision of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Masahiko YazawaDivision of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Junki KoikeDepartment of Diagnostic Pathology, St. Marianna University School of Medicine, Kawasaki, Japan.
Kengo FuruichiDepartment of Nephrology, Kanazawa Medical University School of Medicine, Uchinada, Japan.
Masahiko KawabataDepartment of Internal Medicine, Toyama Prefectural Central Hospital, Toyama, Japan.
Hitoshi YokoyamaDepartment of Nephrology, Kanazawa Medical University School of Medicine, Uchinada, Japan.
Tadashi SofueDivision of Nephrology and Dialysis, Department of Cardiorenal and Cerebrovascular Medicine, Kagawa University, Kagawa, Japan.
Emi IbukiDepartment of Diagnostic Pathology, Kagawa University, Kagawa, Japan.
Shinichi NishiDivision of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.
St. Marianna University School of Medicine · JPToho University · JPKagawa University · JPKanazawa Medical University · JPKobe University · JPToyama Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are certain criteria for selecting living kidney donors. However, the association between clinical characteristics of these criteria and kidney biopsy findings in living kidney donors have not yet been elucidated. Thus, we investigated the association between kidney biopsy findings and clinical characteristics defined in the Japanese guidelines for living kidney donors.

methodsA retrospective multicentre study was conducted on donors and their recipients who underwent kidney transplantation between July 2014 and June 2017. Multiple linear regression analysis and multiple logistic regression analysis were performed to investigate the association between biopsy findings and clinical characteristics.

resultsA total of 240 donors and 240 recipients were included. Age was significantly correlated with global glomerulosclerosis and intimal thickening in multiple linear regression analysis and multiple logistic regression analysis, whereas diabetes was correlated with tubular atrophy in multiple linear regression analysis after multiple imputation and multiple logistic regression analysis.

conclusionsAmongst the clinical factors investigated in our study, age was positively correlated and diabetes was possibly correlated with kidney tissue injury in living kidney donors. Age and diabetes may be more important for selecting suitable living kidney donors than other clinical factors.

Indexed as

Kidney DiseasesKidney TransplantationBiopsyHumansKidneyLiving DonorsNephrectomyRetrospective StudiesTissue DonorsArteriolar hyalinosisGlobal glomerulosclerosisIntimal thickeningKidney transplantationLiving kidney donorTubular atrophy

Identifiers

PMID35064519
OpenAlexW4206941552

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.