ArticleEuropean radiology2022
Diagnostic performance of electron-density dual-energy CT in detection of cervical disc herniation in comparison with standard gray-scale CT and virtual non-calcium images.
Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 18 citations in OpenAlex.
- Improved interobserver agreement for perihematomal edema measurement using dual-layer spectral CT electron density imaging in intracerebral hemorrhage.Emergency radiology · 2026Article
- Detection of lumbar disc herniation and degeneration using photon-counting detector CT with virtual non-calcium imaging.European radiology · 2026Article
- Spectral CT electron density for evaluation of lumbar intervertebral disk degeneration.PloS one · 2026Article
- Electron Density Dual-energy CT for Liver Metastasis Detection Compared with Conventional and Virtual Monoenergetic Images at 40 keV.Current medical imaging · 2026Observational
- Assessment of Intervertebral Lumbar Disk Herniation: Accuracy of Dual-Energy CT Compared to MRI.Journal of clinical medicine · 2025Article
- Dual-energy computed tomography-derived electron density in the differential diagnosis of focal hepatic lesions: initial experience.Quantitative imaging in medicine and surgery · 2025Article
- Dual-layer spectral detector CT electron density imaging: impressive technology for imaging characteristics of ground-glass nodules.Quantitative imaging in medicine and surgery · 2025Article
- Improved visualization of electron-density dual-energy computed tomography for lumbar disc disease over the standard gray-scale type and virtual noncalcium imaging.Quantitative imaging in medicine and surgery · 2025Article
- Anterior Disc Displacement of Temporomandibular Joint: Imaging Diagnosis and Multidisciplinary Treatment.International journal of general medicine · 2025Review
- Application of dual-energy CT in assessing the efficacy of nasopharyngeal carcinoma and diagnosing metastatic lymph nodes.Frontiers in oncology · 2025Article
- Using Key Predictors in an SVM Model for Differentiating Spinal Fractures and Herniated Intervertebral Discs in Preoperative Anesthesia Evaluation.Diagnostics (Basel, Switzerland) · 2024Article
- Electron density dual-energy CT can improve the detection of lumbar disc herniation with higher image quality than standard and virtual non-calcium images.European radiology · 2024Article
- Chances and challenges of photon-counting CT in musculoskeletal imaging.Skeletal radiology · 2024Review
- Characterization of Normal Bone in the Equine Distal Limb with Effective Atomic Number and Electron Density Determined with Single-Source Dual Energy and Detector-Based Spectral Computed Tomography.Animals : an open access journal from MDPI · 2024Article
- Diagnostic performance of dual-energy CT with electron-density reconstruction for lumbar disc herniation.SA journal of radiology · 2024Article
- The utility of virtual monochromatic dual-energy computed tomography (DECT) in meniscal imaging: a technical evaluation.Polish journal of radiology · 2024Article
- Dual-Energy CT in Cardiothoracic Imaging: Current Developments.Diagnostics (Basel, Switzerland) · 2023Review
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8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the diagnostic performance of dual-energy CT (DECT) with electron-density (ED) image reconstruction compared with standard CT (SC) and virtual non-calcium (VNCa) image CT reconstruction for detecting cervical disc herniation.
methodsThis cross-sectional study was approved by the IRB. We enrolled 64 patients (336 intervertebral discs from C2/3 to C7/T1; mean age, 55 years; 17 women and 47 men) who underwent DECT with spectral reconstruction and 3-T MRI within 2 weeks between January 2018 and June 2020. Four radiologists independently evaluated the first image set of randomized SC, VNCa, and ED images to detect cervical disc herniation. After 8 weeks, the readers re-evaluated the second and the last image sets with an 8-week interval. MRI evaluations performed by two other experienced served as the reference standard. Comparing diagnostic performance between each images set was evaluated by a generalized estimating equation.
resultsA total of 233 cervical disc herniations were noted on MRI. For detecting cervical disc herniation, electron-density images showed higher sensitivity (94% [219/233; 95% CI, 90-97] vs. 76% [177/233; 70-81] vs. 69% [160/233; 62-76]) (p < 0.001) and similar specificity (90% [93/103; 83-95] vs. 89% [92/103; 82-96] vs. 90% [93/103; 83-95]) (p > 0.05) as SC and VNCa images, respectively. Inter-reader agreement for cervical disc herniation calculated among the four readers was moderate for all image sets (κ = 0.558 for ED, κ = 0.422 for SC, and κ = 0.449 for VNCa).
conclusionDECT with ED reconstruction can improve cervical disc herniation detection and diagnostic confidence compared with SC and VNCa images. KEY POINTS: • Intervertebral discs with high material density are well visualized on electron-density images obtained from dual-energy CT. • Electron-density images showed much higher sensitivity and diagnostic accuracy than standard CT and virtual non-calcium images for the detection of cervical disc herniation. • Electron-density images can have false-negative results, especially for disc herniation with high signal intensity on T2W images and can show pseudo-disc extrusion at the lower cervical spine.
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