ReviewNature reviews. Endocrinology2022
The role of sugar-sweetened beverages in the global epidemics of obesity and chronic diseases.
Review in Nature reviews. Endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 468 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
468 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Ultra-Processed Food Consumption and Cancer Risk: An Umbrella Review of Systematic Reviews and Meta-Analyses.Journal of food science · 2026Pooled it
- Comprehensive review of carbonated soft drink consumption rates and their public health importance.BMC public health · 2026Pooled it
- Health Effects of Sugar-Sweetened and Artificially Sweetened Beverages: Umbrella Review and Evidence-Based Consensus Statement of the Korean Diabetes Association and the Korean Nutrition Society.Diabetes & metabolism journal · 2026Pooled it
- Sweetened beverages and cardiovascular outcomes: an umbrella review of mortality and health outcomes.Nutrition journal · 2025Pooled it
- Impact of sugar-sweetened beverages on salivary parameters: A systematic review & meta-analysis.Evidence-based dentistry · 2025Pooled it
- Beverage consumption on bone and joint disorders: an umbrella review.Journal of global health · 2025Pooled it
- Impact of policies restricting advertising, promotion, and sponsorship of sugar-sweetened beverages: A systematic review.Revista peruana de medicina experimental y salud publica · 2025Pooled it
- Umbrella Review of Systematic Reviews and Meta-Analyses on the Consumption of Different Food Groups and the Risk of Overweight and Obesity.Nutrients · 2025Pooled it
- Brain and physiological responses to flavored waters with different sweeteners: a randomized crossover study in healthy young adults.The American journal of clinical nutrition · 2026Trial
- Trial
- Determinants of Infant and Young Child Feeding Practices of Children With Severe Acute Malnutrition in Agrarian and Pastoralist Settings of Ethiopia.Maternal & child nutrition · 2026Trial
- Trial
- Water First School Water Promotion and Access Intervention: A Cost Analysis Study.Journal of the Academy of Nutrition and Dietetics · 2025Trial
- A digital behavioral intervention to reduce sugar-sweetened beverage consumption: a randomized, controlled trial.The American journal of clinical nutrition · 2025Trial
- Trial
- Effects of Oral Xylitol, Sucrose, and Acesulfame Potassium on Total Energy Intake During a SubsequentNutrients · 2025Trial
- Trial
- Romboutsia ilealis related metabolite OAA controls obesity and lipid metabolism through PSMD3-mediated degradation of YTHDF2.Cell death and differentiation · 2026Article
- "Association of Knowledge, Dietary Behaviors, and Attitudes Toward Hair Problems Among the Population in the Chattogram Division, Bangladesh: A Cross-Sectional Study".Health science reports · 2026Article
- Comparison of Mineral and Trace Element Contents in Commercial Zero-Labeled and Regular Non-Alcoholic Beverages.Biological trace element research · 2026Article
408 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sugar-sweetened beverages (SSBs) are a major source of added sugars in the diet. A robust body of evidence has linked habitual intake of SSBs with weight gain and a higher risk (compared with infrequent SSB consumption) of type 2 diabetes mellitus, cardiovascular diseases and some cancers, which makes these beverages a clear target for policy and regulatory actions. This Review provides an update on the evidence linking SSBs to obesity, cardiometabolic outcomes and related cancers, as well as methods to grade the strength of nutritional research. We discuss potential biological mechanisms by which constituent sugars can contribute to these outcomes. We also consider global trends in intake, alternative beverages (including artificially-sweetened beverages) and policy strategies targeting SSBs that have been implemented in different settings. Strong evidence from cohort studies on clinical outcomes and clinical trials assessing cardiometabolic risk factors supports an aetiological role of SSBs in relation to weight gain and cardiometabolic diseases. Many populations show high levels of SSB consumption and in low-income and middle-income countries, increased consumption patterns are associated with urbanization and economic growth. As such, more intensified policy efforts are needed to reduce intake of SSBs and the global burden of obesity and chronic diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.